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Promethazine

Catalog No. Promethazine Name Wikipedia.org
CAS Number 60-87-7 Website http://www.wikipedia.org/
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SYNONYMS

IUPAC name
dimethyl[1-(10H-phenothiazin-10-yl)propan-2-yl]amine
IUPAC Traditional name
promethazine

DATABASE IDS

CHEMBL 643
Unique Ingredient Identifier FF28EJQ494
Wikipedia Title Promethazine
Chemspider ID 4759
PubChem CID 4927
ATC CODE R06AD05
DrugBank ID DB01069
CHEBI ID 8461
Medline Plus a682284
ATC CODE R06AD02
CAS Number 60-87-7
ATC CODE D04AA10
KEGG ID D00494

PROPERTIES

Admin Routes Oral, rectal, IV, IM, topical
Bioavailability 88% absorbed but after first-pass metabolism reduced to 25% absolute bioavailability
Excretion Renal and biliary
Half Life 16-19 hours
Legal Status
(injection POM(UK))
Legal Status Rx-only (US)
Metabolism Hepatic glucuronidation and sulfoxidation
Pregnancy Category C (US)
Pregnancy Category C (Australia)
Protein Bound 93%

DETAILS

Description (English)

REFERENCES