Nicotine

• Catalog No.: Nicotine
• CAS Number: 54-11-5
• M. F.: C10H14N2
• M. W.: 162.23156

SYNONYMS

• IUPAC name: 3-[(2S)-1-methylpyrrolidin-2-yl]pyridine
• IUPAC Traditional name: nicoderm CQ
• Brand Name: Nicorette, Nicotrol

DATABASE IDS

• IUPHAR ligand ID: 2585
• DrugBank ID: DB00184
• ATC CODE: QP53AX13
• Wikipedia Title: Nicotine
• CHEBI ID: 17688
• Chemspider ID: 80863
• KEGG ID: D03365
• PubChem CID: 942
• CHEMBL: 3
• Unique Ingredient Identifier: 6M3C89ZY6R
• ATC CODE: N07BA01
• CAS Number: 54-11-5

PROPERTIES

• Admin Routes: smoked (as smoking tobacco, mapacho, etc.), insufflated (as tobacco snuff or nicotine nasal spray), chewed (as nicotine gum, tobacco gum or chewing tobacco), transdermal (as nicotine patch, nicogel or topical tobacco paste), intrabuccal (as dipping tobacco, snuffs, dissolvable tobacco or creamy snuff), vaporized (as electronic cigarette, etc.), directly inhaled (as nicotine inhaler), oral (as nicotini), buccal (as snus)
• Bioavailability: 20 to 45% (oral)
• Dependency Liability: Moderate
• Half Life: 2 hours; 20 hours active metabolite (cotinine)
• Legal Status: Unscheduled (Australia)
• Legal Status: GSL (UK)
• Legal Status: OTC (US)
• Metabolism: hepatic
• Pregnancy Category: D (US)
• Boiling Point: 247°C (476.6°F)
• Density: 1.01 g/cm^3
• Melting Point: -79°C (-110.2°F)