Heroin

• Catalog No.: Heroin
• CAS Number: 561-27-3
• M. F.: C21H23NO5
• M. W.: 369.41102

SYNONYMS

• IUPAC name: (1S,5R,13R,14S,17R)-14-(acetyloxy)-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^1,^1^3.0^5,^1^7.0^7,^1^8]octadeca-7,9,11(18),15-tetraen-10-yl acetate
• IUPAC Traditional name: (1S,5R,13R,14S,17R)-14-(acetyloxy)-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^1,^1^3.0^5,^1^7.0^7,^1^8]octadeca-7,9,11(18),15-tetraen-10-yl acetate
• Synonyms: Acetomorphine; Morphine diacetate; Diamorphine; (Dual) Acetylated morphine; Diacetylmorphine

DATABASE IDS

• Chemspider ID: 4575379
• ATC CODE: N07BC06
• DrugBank ID: DB01452
• CHEBI ID: 27808
• CAS Number: 561-27-3
• PubChem CID: 5462328
• Wikipedia Title: Heroin
• CHEMBL: 459324
• Unique Ingredient Identifier: 8H672SHT8E

PROPERTIES

• Admin Routes: Inhalation, Transmucosal, Intravenous, Oral, Intranasal, Rectal, Intramuscular
• Bioavailability: <35% (oral), 44–61% (inhaled)
• Dependency Liability: High
• Excretion: 90% renal as glucuronides, rest biliary
• Half Life: <10 minutes
• Legal Status: S9 (Australia)
• Legal Status: Schedule I (Canada)
• Legal Status: Class A (UK)
• Legal Status: Schedule I (US)
• Metabolism: hepatic
• Pregnancy Category: Not yet classified, but studies have shown a risk of abnormalities, hepatitis, malnutrition, and many other effects.
• Protein Bound: 0% (morphine metabolite 35%)