Fentanyl

• Catalog No.: Fentanyl
• CAS Number: 437-38-7
• M. F.: C22H28N2O
• M. W.: 336.47052

SYNONYMS

• IUPAC name: N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide
• IUPAC Traditional name: fentanyl
• Brand Name: Sublimaze

DATABASE IDS

• CAS Number: 437-38-7
• CHEMBL: 596
• CHEBI ID: 119915
• IUPHAR ligand ID: 1626
• ATC CODE: N01AH01
• Chemspider ID: 3228
• Wikipedia Title: Fentanyl
• ATC CODE: N02AB03
• Unique Ingredient Identifier: UF599785JZ
• DrugBank ID: DB00813
• KEGG ID: D00320
• PubChem CID: 3345

PROPERTIES

• Admin Routes: TD, IM, IV, oral, sublingual, buccal
• Bioavailability: 92% (transdermal); 89% (intranasal); 50% (buccal); 33% (ingestion)
• Dependency Liability: Moderate - High
• Excretion: 60% Urinary (metabolites, <10% unchanged drug)
• Half Life: (IV)= 2.5 minutes ; Intranasal = 6.5 mins ; Transdermal = 7 hours (range 3–12 h)
• Legal Status: Class A (UK)
• Legal Status: Schedule II (US)
• Metabolism: hepatic, primarily by CYP3A4
• Pregnancy Category: C (US)
• Protein Bound: 80-85%
• Melting Point: 87.5°C (189.5°F)