Domperidone

• Catalog No.: Domperidone
• CAS Number: 57808-66-9
• M. F.: C22H24ClN5O2
• M. W.: 425.91126

SYNONYMS

• IUPAC name: 5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl)propyl]piperidin-4-yl}-2,3-dihydro-1H-1,3-benzodiazol-2-one
• IUPAC Traditional name: motilium
• Brand Name: Motilium

DATABASE IDS

• Unique Ingredient Identifier: 5587267Z69
• IUPHAR ligand ID: 965
• CAS Number: 57808-66-9
• CHEBI ID: 31515
• Wikipedia Title: Domperidone
• DrugBank ID: DB01184
• PubChem CID: 3151
• Chemspider ID: 3039
• ATC CODE: QP51AX24
• ATC CODE: A03FA03
• KEGG ID: D01745
• CHEMBL: 219916

PROPERTIES

• Admin Routes: Oral, intravenous, rectal
• Bioavailability: High
• Excretion: Breast milk, renal
• Half Life: 7 hours
• Legal Status: Not approved for use or sale: US; prescription medicine (POM): India, Australia, Canada, Israel; Over the Counter (OTC): UK (Pharmacy only), Belgium, Egypt, Ireland, Italy, Japan, Netherlands, South Africa, Switzerland, China, Russia, Slovakia, Thailand, Malta, South Korea, and Romania
• Metabolism: Hepatic and intestinal (first-pass)
• Pregnancy Category: Not classified (US)
• Protein Bound: 91–93%