Ciclosporin

• Catalog No.: Ciclosporin
• CAS Number: 59865-13-3
• M. F.: C62H111N11O12
• M. W.: 1202.61124

SYNONYMS

• IUPAC name: (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(1R,2R)-1-hydroxy-2-methylhex-4-en-1-yl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-bis(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecone
• IUPAC Traditional name: (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(1R,2R)-1-hydroxy-2-methylhex-4-en-1-yl]-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecone
• Brand Name: Neoral, Sandimmune

DATABASE IDS

• KEGG ID: D00184
• ATC CODE: S01XA18
• CAS Number: 59865-13-3
• CHEMBL: 160
• Unique Ingredient Identifier: 83HN0GTJ6D
• PubChem CID: 5284373
• Chemspider ID: 4447449
• DrugBank ID: DB00091
• Wikipedia Title: Ciclosporin
• Medline Plus: a601207
• ATC CODE: L04AD01

PROPERTIES

• Admin Routes: Oral, IV, ophthalmic
• Bioavailability: Variable
• Excretion: Biliary
• Half Life: Variable (about 24 hours)
• Legal Status: S4 (Australia)
• Legal Status: POM (UK)
• Legal Status: Rx-only (US)
• Metabolism: Hepatic
• Pregnancy Category: C (US)
• Pregnancy Category: C (Australia)