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Chlorpromazine

Catalog No. Chlorpromazine Name Wikipedia.org
CAS Number 50-53-3 Website http://www.wikipedia.org/
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SYNONYMS

IUPAC name
[3-(2-chloro-10H-phenothiazin-10-yl)propyl]dimethylamine
IUPAC Traditional name
chlorpromazine

DATABASE IDS

CHEBI ID 3647
CAS Number 50-53-3
Medline Plus a682040
ATC CODE N05AA01
DrugBank ID DB00477
PubChem CID 2726
Unique Ingredient Identifier U42B7VYA4P
CHEMBL 71
Chemspider ID 2625
KEGG ID D00270
IUPHAR ligand ID 83
Wikipedia Title Chlorpromazine

PROPERTIES

Admin Routes Oral, rectal (suppository), IM, IV infusion
Bioavailability Oral, 30 to 50% (interindividual variations 10–70%)
Excretion Biliary and renal, as metabolites (only traces of unchanged drug)
Half Life 16 to 30 hours. In long term treatment, CPZ induces its own metabolism
Legal Status Rx-only
Metabolism Hepatic, mostly CYP2D6-mediated
Pregnancy Category C—only when benefit for the mother exceeds risk to unborn child

DETAILS

Description (English)

REFERENCES