| Item |
Information |
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Drug Groups
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approved |
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Description
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A thioxanthine used as an antipsychotic agent. Its effects are similar to the phenothiazine antipsychotics. [PubChem] |
| Indication |
For the management of schizophrenia. |
| Pharmacology |
Thiothixene is an antipsychotic of the thioxanthene series. Navane possesses certain chemical and pharmacological similarities to the piperazine phenothiazines and differences from the aliphatic group of phenothiazines. Although widely used in the treatment of schizophrenia for several decades, thiothixene is seldom used today in favor of atypical antipsychotics such as risperidone. |
| Toxicity |
Symptoms of overdose include central nervous system depression, coma, difficulty swallowing, dizziness, drowsiness, head tilted to the side, low blood pressure, muscle twitching, rigid muscles, salivation, tremors, walking disturbances, and weakness. |
| Affected Organisms |
| • |
Humans and other mammals |
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| Biotransformation |
Hepatic. |
| Half Life |
10-20 hours |
| External Links |
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