Item |
Information |
Drug Groups
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approved |
Description
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One of the histamine H1 antagonists with little sedative action. It is used in treatment of hay fever, rhinitis, allergic dermatoses, and pruritus. [PubChem] |
Indication |
Pheniramine is an antihistamine used to treat allergic conditions such as hay fever or urticaria. |
Pharmacology |
Pheniramine is an antihistamine used to treat allergic conditions such as hay fever or urticaria. It is generally sold in combination with other medications, rather than as a stand-alone drug. Allergies are caused by an excessive type 1 hypersensitivity response of the body to allergens, mediated by inappropriate histamine signalling. By inhibiting the binding of histamine, antihistamines decrease the normal histamine response from cells, consequently decreasing allergic symptoms. |
Affected Organisms |
• |
Humans and other mammals |
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Biotransformation |
Hepatic hydroxylation, demethylation and glucuronidation. |
External Links |
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