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3-Methylfentanyl

Catalog No. DB01571 Name DrugBank
CAS Number 42045-86-3 Website http://www.ualberta.ca/
M. F. C23H30N2O Telephone (780) 492-3111
M. W. 350.4971 Fax (780) 492-1071
Purity Email david.wishart@ualberta.ca
Storage Chembase ID: 1355

SYNONYMS

IUPAC name
N-[3-methyl-1-(2-phenylethyl)piperidin-4-yl]-N-phenylpropanamide
IUPAC Traditional name
3-methylfentanyl
Synonyms
DEA No. 9813
mefentanyl
3-MF

DATABASE IDS

CAS Number 42045-86-3
PubChem CID 61996
PubChem SID 46509149

PROPERTIES

DETAILS

Description (English)
Item Information
Drug Groups illicit; experimental
Description 3-Methylfentanyl (3-MF, mefentanyl) is an opioid analgesic that is an analogue of fentanyl. 3-Methylfentanyl is one of the most potent drugs that has been widely sold on the black market, estimated to be between 400-6000 times stronger than morphine depending on which isomer is used (with cis isomer being the more potent one). 3-Methylfentanyl was first discovered in 1974 [4] and subsequently appeared on the street as an alternative to the clandestinely produced fentanyl analogue α-methylfentanyl. However it quickly became apparent that 3-methylfentanyl was much more potent than α-methylfentanyl, and corespondingly even more dangerous. [Wikipedia]
Pharmacology 3-Methylfentanyl has similar effects to fentanyl, but is far more potent due to increased binding affinity to its target site. Since fentanyl itself is already highly potent, 3-methylfentanyl is extremely dangerous when used recreationally, and has resulted in many deaths among opiate addicts using the drug.
Toxicity 3-Methylfentanyl has resulted in many deaths among opiate addicts using the drug.
Affected Organisms
Humans and other mammals
External Links
Wikipedia

REFERENCES