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Tenocyclidine

Catalog No. DB01520 Name DrugBank
CAS Number 21500-98-1 Website http://www.ualberta.ca/
M. F. C15H23NS Telephone (780) 492-3111
M. W. 249.41482 Fax (780) 492-1071
Purity Email david.wishart@ualberta.ca
Storage Chembase ID: 1307

SYNONYMS

IUPAC name
1-[1-(thiophen-2-yl)cyclohexyl]piperidine
IUPAC Traditional name
tenocyclidine
Synonyms
TCP

DATABASE IDS

PubChem CID 62751
CAS Number 21500-98-1
PubChem SID 46505124

PROPERTIES

DETAILS

Description (English)
Item Information
Drug Groups illicit; experimental
Description Tenocyclidine (TCP, thienyl cyclohexylpiperidine) is a dissociative anesthetic drug with stimulant and hallucinogenic effects. It is similar in effects to phencyclidine but is considerably more potent. Due to its similarity in effects to PCP, TCP was placed into the Schedule I list of illegal drugs in the 1970s, although it was only briefly abused in the 1970s and 1980s and is now little known. [Wikipedia]
Indication Because of its high affinity for the phencyclidine binding site on the NMDA receptor, the 3H radiolabelled form of tenocyclidine is widely used in research into NMDA receptors.
Pharmacology Tenocyclidine (TCP) has slightly different binding properties to phencyclidine (PCP), with more affinity for NMDA receptors but less affinity for sigma receptors.
Affected Organisms
Humans and other mammals
External Links
Wikipedia

REFERENCES