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MeOSuc-Ala-Ala-Pro-Val-paranitroanilide_Molecular_structure_CAS_70967-90-7)
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MeOSuc-Ala-Ala-Pro-Val-paranitroanilide

Catalog No. 03PNA094 Name MP Biomedicals
CAS Number 70967-90-7 Website http://www.mpbio.com
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SYNONYMS

IUPAC name
methyl 3-{[(1S)-1-{[(2S)-1-[(2S)-2-{[(1S)-2-methyl-1-[(4-nitrophenyl)carbamoyl]propyl]carbamoyl}pyrrolidin-1-yl]-1-oxopropan-2-yl]carbamoyl}ethyl]carbamoyl}propanoate
IUPAC Traditional name
methyl 3-{[(1S)-1-{[(2S)-1-[(2S)-2-{[(1S)-2-methyl-1-[(4-nitrophenyl)carbamoyl]propyl]carbamoyl}pyrrolidin-1-yl]-1-oxopropan-2-yl]carbamoyl}ethyl]carbamoyl}propanoate
Synonyms
MeOSuc-AAPV-PNA
MeOSuc-Ala-Ala-Pro-Val-PNA

DATABASE IDS

CAS Number 70967-90-7

PROPERTIES

Certificate of Analysis Download
MSDS Link Download

DETAILS

Description (English)
A specific chromogenic substrate for human neutrophil elastase (Kcat/Km = 120,000 vs. 2700 for pancreatic elastase). Cleavage can be monitored at ~410 nm. Sold on the basis of substrate content.

REFERENCES

  • Thornberry, N.A. et al., Science, 281:1312 (1998).
  • Thornberry, N.A. et al., J. Biol. Chem., 272:17907 (1997).
  • Barrett, A.J., et al. 1989. Biochim. J. 260, 259.
  • Nakajima, K., et al. 1979. J. Biol. Chem. 254, 4027.