Z-Arg-Gly-Phe-Phe-Pro-4-Methoxy-2-Naphthylamine_Molecular_structure_CAS_)

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Z-Arg-Gly-Phe-Phe-Pro-4-Methoxy-2-Naphthylamine
Catalog No.	03MNA098	Name	MP Biomedicals
CAS Number		Website	http://www.mpbio.com
M. F.	C50H57N9O8	Telephone
M. W.	912.04308	Fax
Purity		Email
Storage		Chembase ID: 106580

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SYNONYMS

IUPAC name

benzyl N-[(1S)-4-carbamimidamido-1-[({[(1S)-1-{[(2S)-1-[(2S)-2-[(4-methoxynaphthalen-2-yl)carbamoyl]pyrrolidin-1-yl]-1-oxo-3-phenylpropan-2-yl]carbamoyl}-2-phenylethyl]carbamoyl}methyl)carbamoyl]butyl]carbamate

IUPAC Traditional name

benzyl N-[(1S)-4-carbamimidamido-1-[({[(1S)-1-{[(2S)-1-[(2S)-2-[(4-methoxynaphthalen-2-yl)carbamoyl]pyrrolidin-1-yl]-1-oxo-3-phenylpropan-2-yl]carbamoyl}-2-phenylethyl]carbamoyl}methyl)carbamoyl]butyl]carbamate

Synonyms

Z-Arg-Gly-Phe-Phe-Pro-MNA

Z-RGFFP-MNA

DATABASE IDS

PROPERTIES

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DETAILS

Description (English)

A fluorogenic/colorimetric substrate for Cathespin D. Suitable for either colorimetric or fluorometric assay. Cathepsin D hydrolyzes the Phe-Phe bond. Requires dipeptidyl aminopeptidase II to free 4-methoxy-b-naphthylamine (MNA).

REFERENCES

Lojda, Z., et al., Biochem., Biophys. Res. Comm., 148:335 (1987)
Gulmik,S. et al., Mol. Bio., 277:265