Z-Val-Asp(OMe)-Val-Ala-Asp(OMe)-Fluoromethylketone_Molecular_structure_CAS_)

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Z-Val-Asp(OMe)-Val-Ala-Asp(OMe)-Fluoromethylketone
Catalog No.	03FK016	Name	MP Biomedicals
CAS Number		Website	http://www.mpbio.com
M. F.	C32H46FN5O11	Telephone
M. W.	695.7329432	Fax
Purity		Email
Storage		Chembase ID: 106510

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SYNONYMS

IUPAC name

methyl (3S)-3-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-3-methylbutanamido]-4-methoxy-4-oxobutanamido]-3-methylbutanamido]propanamido]-5-fluoro-4-oxopentanoate

IUPAC Traditional name

methyl (3S)-3-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-3-methylbutanamido]-4-methoxy-4-oxobutanamido]-3-methylbutanamido]propanamido]-5-fluoro-4-oxopentanoate

Synonyms

Z-Val-Asp(OMe)-Val-Ala-Asp(OMe)-FMK

Z-VD(OMe)VAD(OMe)-FMK

DATABASE IDS

PROPERTIES

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DETAILS

Description (English)

A cell-permeable and irreversible inhibitor of caspase-2 (ICH-1)

REFERENCES

Zhuang, S. et al., Am. J. Physiol. Cell. Physiol., 279(2):C341 (2000).
Talanian, R.V. et al., J. Biol. Chem., 272(15):9677 (1997).
Gregoli, P.A., and Bondurant, M.C. 1999. J. Cell Physiol. 178, 133.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.