Z-Tyr-Val-Ala-Asp(OMe)-Fluoromethylketone_Molecular_structure_CAS_)

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Z-Tyr-Val-Ala-Asp(OMe)-Fluoromethylketone
Catalog No.	03FK013	Name	MP Biomedicals
CAS Number		Website	http://www.mpbio.com
M. F.	C31H39FN4O9	Telephone
M. W.	630.6611632	Fax
Purity		Email
Storage		Chembase ID: 106507

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SYNONYMS

IUPAC name

methyl (3S)-3-[(2S)-2-[(2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-3-(4-hydroxyphenyl)propanamido]-3-methylbutanamido]propanamido]-5-fluoro-4-oxopentanoate

IUPAC Traditional name

methyl (3S)-3-[(2S)-2-[(2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-3-(4-hydroxyphenyl)propanamido]-3-methylbutanamido]propanamido]-5-fluoro-4-oxopentanoate

Synonyms

Z-Tyr-Val-Ala-Asp(OMe)-FMK

Z-YVAD(OMe)-FMK

DATABASE IDS

PROPERTIES

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MSDS Link	Download

DETAILS

Description (English)

A potent, cell-permeable, and irreversible inhibitor of caspase-1 (ICE), caspase-4, and caspase-5.

REFERENCES

Thornberry, N. et al., Persp. in Drug Disc. and Design, 2:389 (1994).
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Eldadah, B.A., et al. 1997. J. Neurosci. 17, 6105.