Ac-Ile-Glu-Thr-Asp-7-Amino-4-Methylcoumarin_Molecular_structure_CAS_)

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Ac-Ile-Glu-Thr-Asp-7-Amino-4-Methylcoumarin
Catalog No.	03AMC140	Name	MP Biomedicals
CAS Number		Website	http://www.mpbio.com
M. F.	C31H41N5O12	Telephone
M. W.	675.68354	Fax
Purity		Email
Storage		Chembase ID: 106442

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SYNONYMS

IUPAC name

(4S)-4-{[(1S,2R)-1-{[(1S)-2-carboxy-1-[(4-methyl-2-oxo-2H-chromen-7-yl)carbamoyl]ethyl]carbamoyl}-2-hydroxypropyl]carbamoyl}-4-[(2S,3S)-2-acetamido-3-methylpentanamido]butanoic acid

IUPAC Traditional name

(4S)-4-{[(1S,2R)-1-{[(1S)-2-carboxy-1-[(4-methyl-2-oxochromen-7-yl)carbamoyl]ethyl]carbamoyl}-2-hydroxypropyl]carbamoyl}-4-[(2S,3S)-2-acetamido-3-methylpentanamido]butanoic acid

Synonyms

Ac-Ile-Glu-Thr-Asp-AMC

Ac-IETD-AMC

DATABASE IDS

PROPERTIES

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DETAILS

Description (English)

A fluorogenic substrate for Caspase-8 and Granzyme B.

REFERENCES

Thornberry, H.A. et al., Science, 281:1312 (1998).
Talanian, R.V. et al., J. Biol. Chem., 272:9677 (1997).