Suc-Leu-Tyr-7-Amino-4-Methylcoumarin_Molecular_structure_CAS_94367-20-1)

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Suc-Leu-Tyr-7-Amino-4-Methylcoumarin
Catalog No.	03AMC117	Name	MP Biomedicals
CAS Number	94367-20-1	Website	http://www.mpbio.com
M. F.	C29H33N3O8	Telephone
M. W.	551.58762	Fax
Purity		Email
Storage		Chembase ID: 106434

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SYNONYMS

IUPAC name

3-{[(1S)-1-{[(1S)-2-(4-hydroxyphenyl)-1-[(4-methyl-2-oxo-2H-chromen-7-yl)carbamoyl]ethyl]carbamoyl}-3-methylbutyl]carbamoyl}propanoic acid

IUPAC Traditional name

3-{[(1S)-1-{[(1S)-2-(4-hydroxyphenyl)-1-[(4-methyl-2-oxochromen-7-yl)carbamoyl]ethyl]carbamoyl}-3-methylbutyl]carbamoyl}propanoic acid

Synonyms

Suc-Leu-Tyr-AMC

Suc-LY-AMC

DATABASE IDS

CAS Number

94367-20-1

PROPERTIES

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MSDS Link	Download

DETAILS

Description (English)

A fluorogenic substrate for the quantitative determination of Calpain Isozymes I, Calpain Isozymes II and E. Coli Protease Ti. Also suitable for measuring the peptidase activity of the 20S proteasome. Typical concentrations range from 10 - 100 μM, depending on assay conditions. PROTECT FROM LIGHT. PROTECT FROM MOISTURE.
Excitation max.: ~380 nm
Emission max.: ~460 nm

REFERENCES

Sasaki, T. et al., J. Biol. Chem., 259:12489 (1984).
Woo, K.M. et al., J. Biol. Chem., 264:2088 (1989).
Seol, J.H., et al. 1989. FEBS Lett. 247, 197.