MeOSuc-Ala-Ala-Pro-Val-7-Amino-4-Methylcoumarin_Molecular_structure_CAS_72252-90-5)

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MeOSuc-Ala-Ala-Pro-Val-7-Amino-4-Methylcoumarin
Catalog No.	03AMC094	Name	MP Biomedicals
CAS Number	72252-90-5	Website	http://www.mpbio.com
M. F.	C31H41N5O9	Telephone
M. W.	627.68534	Fax
Purity		Email
Storage		Chembase ID: 106428

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SYNONYMS

IUPAC name

methyl 3-{[(1S)-1-{[(2S)-1-[(2S)-2-{[(1S)-2-methyl-1-[(4-methyl-2-oxo-2H-chromen-7-yl)carbamoyl]propyl]carbamoyl}pyrrolidin-1-yl]-1-oxopropan-2-yl]carbamoyl}ethyl]carbamoyl}propanoate

IUPAC Traditional name

methyl 3-{[(1S)-1-{[(2S)-1-[(2S)-2-{[(1S)-2-methyl-1-[(4-methyl-2-oxochromen-7-yl)carbamoyl]propyl]carbamoyl}pyrrolidin-1-yl]-1-oxopropan-2-yl]carbamoyl}ethyl]carbamoyl}propanoate

Synonyms

MeOSuc-AAPV-AMC

MeOSuc-Ala-Ala-Pro-Val-AMC

DATABASE IDS

CAS Number

72252-90-5

PROPERTIES

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DETAILS

Description (English)

A sensitive fluorogenic substrate for the quantitative determination of human leukocyte and porcine pancreatic elastase (Km = 140 μM; kcat/Km = 120,000 M^-1 s^-1). Not hydrolysed by cathepsin G.

REFERENCES

Stein, R. L. et al., Biochem., 25:5414 (1986).
Del Mar, E.G. et al., Biochem., 19:468 (1980).
Castillo, M.J. et al., Anal. Biochem., 99:53 (1979).
Barrett, A.J. 1981. Methods Enzymol. 80, 581.
Nakajima, K., et al. 1979. J. Biol. Chem. 254, 4027.