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Z-Arg-Arg-7-Amino-4-Methylcoumarin

Catalog No. 03AMC051 Name MP Biomedicals
CAS Number 136132-67-7 Website http://www.mpbio.com
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SYNONYMS

IUPAC name
benzyl N-[(1S)-4-carbamimidamido-1-{[(1S)-4-carbamimidamido-1-[(4-methyl-2-oxo-2H-chromen-7-yl)carbamoyl]butyl]carbamoyl}butyl]carbamate
IUPAC Traditional name
benzyl N-[(1S)-4-carbamimidamido-1-{[(1S)-4-carbamimidamido-1-[(4-methyl-2-oxochromen-7-yl)carbamoyl]butyl]carbamoyl}butyl]carbamate
Synonyms
Z-Arg-Arg-AMC
Z-RR-AMC

DATABASE IDS

CAS Number 136132-67-7

PROPERTIES

Certificate of Analysis Download
MSDS Link Download

DETAILS

Description (English)
HYGROSCOPIC. Keep in desiccator. A sensitive fluorogenic substrate for the quantitative determination of cathepsin B activity.
Excitation max.: ~360-380 nm, Emission max.: ~430-460 nm

REFERENCES

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  • Hasnain, S et al., Biol. Chem. Hoppe- Seyler, 373:413 (1992).
  • Smith, R.E. et al., Antican. Res., 8:525 (1988).
  • Hiwasa, T., et al. 1987. FEBS Lett. 211, 23.
  • Manson, R.W., et al. 1985. Biochem. J. 226, 233.
  • Tanaka, M., et al. 1985. Life Sci. 36, 1217.
  • Docherty, K., et al. 1984. J. Biol. Chem. 259, 6041.
  • Barrett, A.J., and Kirschke, H. 1981. Methods Enzymol. 80, 535.
  • Barrett, A.J. 1980. Biochem. J. 187, 909.