Ac-Asp-Glu-Val-Asp-Aldehyde_Molecular_structure_CAS_169332-60-9)

add Ac-Asp-Glu-Val-Asp-Aldehyde to favorite

2D 3D Download Zoom

Ac-Asp-Glu-Val-Asp-Aldehyde
Catalog No.	03AL010	Name	MP Biomedicals
CAS Number	169332-60-9	Website	http://www.mpbio.com
M. F.	C20H30N4O11	Telephone
M. W.	502.4724	Fax
Purity		Email
Storage		Chembase ID: 106373

PRICE

Please log in

SYNONYMS

IUPAC name

(4S)-4-[(2S)-3-carboxy-2-acetamidopropanamido]-4-{[(1S)-1-{[(2S)-1-carboxy-3-oxopropan-2-yl]carbamoyl}-2-methylpropyl]carbamoyl}butanoic acid

IUPAC Traditional name

ac-devd-cho

Synonyms

Ac-DEVD-CHO

Ac-Asp-Glu-Val-Asp-CHO

DATABASE IDS

CAS Number

169332-60-9

PROPERTIES

Certificate of Analysis	Download
MSDS Link	Download

DETAILS

Description (English)

A very potent, specific, and reversible inhibitor of caspase-3 (IC₅₀ = 200 pM), caspase-6, caspase-7, caspase-8, and caspase-10.

REFERENCES

Garcia-Calvo, M. et al., J. Biol. Chem., 273:32608 (1998).
Thornberry, N.A. and Lazebnik, Y. et al., Science, 281:1312 (1998).
Nicholson, D.W. et al., Nature Biotech., 14:297 (1996).
Schlegel, J., et al. 1996. J. Biol. Chem. 271, 1841.
Nicholson, D.W., et al. 1995. Nature 376, 37.