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Ac-Leu-Glu-Thr-Asp-7-Amino-4-trifluoromethylcoumarin_Molecular_structure_CAS_)
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Ac-Leu-Glu-Thr-Asp-7-Amino-4-trifluoromethylcoumarin

Catalog No. 03AFC157 Name MP Biomedicals
CAS Number Website http://www.mpbio.com
M. F. C31H38F3N5O12 Telephone
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Storage Chembase ID: 106360

SYNONYMS

IUPAC name
(4S)-4-{[(1S,2R)-1-{[(1S)-2-carboxy-1-{[2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl]carbamoyl}ethyl]carbamoyl}-2-hydroxypropyl]carbamoyl}-4-[(2S)-2-acetamido-4-methylpentanamido]butanoic acid
IUPAC Traditional name
(4S)-4-{[(1S,2R)-1-{[(1S)-2-carboxy-1-{[2-oxo-4-(trifluoromethyl)chromen-7-yl]carbamoyl}ethyl]carbamoyl}-2-hydroxypropyl]carbamoyl}-4-[(2S)-2-acetamido-4-methylpentanamido]butanoic acid
Synonyms
Ac-LGlutD-AFC
Ac-Leu-Glu-Thr-Asp-AFC

DATABASE IDS

PROPERTIES

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DETAILS

Description (English)
A fluorogenic substrate for Caspase-8.

REFERENCES

  • Thornberry, N.A. et al., Science, 281:1312 (1998).
  • Talanian, R.V. et al., J. Biol. Chem., 272:9677 (1997).