3-METHYLCHOLANTHRENE

• Catalog No.: 02199873
• CAS Number: 56-49-5
• M. F.: C21H16
• M. W.: 268.35174

SYNONYMS

• IUPAC name: 16-methylpentacyclo[11.6.1.0^{2,11}.0^{5,10}.0^{17,20}]icosa-1,3,5,7,9,11,13,15,17(20)-nonaene
• IUPAC Traditional name: methylcholanthrene
• Synonyms: 3-methyl-1,2-dihydrocyclopenta[ij]tetraphene

DATABASE IDS

• CAS Number: 56-49-5
• EC Number: 200-276-4

PROPERTIES

• Boiling Point: 280°C/80 mmHg
• Melting Point: 170-173°C
• European Hazard Symbols: Toxic (T)
• Risk Statements: R:45
• RTECS: FZ3675000
• Safety Statements: S:53-36/37/39-45

DETAILS

Description (English)

Purity: ≥98%
Carcinogen used to induce transformation of cultured cells; used to induce fibrosarcomas and skin carcinomas in laboratory animals.

REFERENCES

• Crowe, N.Y., et al., A critical role for natural killer T cells in immunosurveillance of methylcholanthrene-induced sarcomas. J. Exp. Med. 196, 119-127, (2002)
• Hirai, K., et al., Clonal evolution and progression of 20-methylcholanthrene-induced squamous cell carcinoma of mouse epidermis as revealed by DNA instability and other malignancy markers. Eur. J. Histochem. 45, 319-332, (2001)