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WORTMANNIN

Catalog No. 02195690 Name MP Biomedicals
CAS Number 19545-26-7 Website http://www.mpbio.com
M. F. C23H24O8 Telephone
M. W. 428.43186 Fax
Purity Email
Storage -20°C, Desiccate Chembase ID: 105996

SYNONYMS

IUPAC name
18-(methoxymethyl)-1,5-dimethyl-6,11,16-trioxo-13,17-dioxapentacyclo[10.6.1.0^{2,10}.0^{5,9}.0^{15,19}]nonadeca-2(10),12(19),14-trien-3-yl acetate
IUPAC Traditional name
wortmannin

DATABASE IDS

CAS Number 19545-26-7

PROPERTIES

Certificate of Analysis Download
MSDS Link Download
RTECS CB9641000
Storage Condition -20°C, Desiccate

DETAILS

Description (English)
A fungal metabolite which potently and selectively inhibits phosphatidylinositol 3-kinase. It also inhibits fMLP induced PIP3 and superoxide anion production in guinea pig neutrophils. It blocks insulin metabolic effects in rat adipocytes without affecting the insulin receptor tyrosine kinase activity.

REFERENCES