p-AMIDINOPHENYLMETHYLSULFONYLFLUORIDE HYDROCHLORIDE

• Catalog No.: 02194956
• CAS Number: 74938-88-8
• M. F.: C8H10ClFN2O2S
• M. W.: 252.6936032
• Purity: >75%
• Storage: 2-8°C

SYNONYMS

• IUPAC name: (4-carbamimidoylphenyl)methanesulfonyl fluoride hydrochloride
• IUPAC Traditional name: (4-carbamimidoylphenyl)methanesulfonyl fluoride hydrochloride
• Synonyms: p-APMSF

DATABASE IDS

• CAS Number: 74938-88-8

PROPERTIES

• Purity: >75%
• Storage Condition: 2-8°C

DETAILS

Description (English)

Hydrochloride
Purity: >75%
A stable, non-toxic alternative to DFP or PMSF. Specifically and irreversibly inhibits trypsin-like serine proteases, trypsin, and thrombin. Demonstrates activity on factor Xa, plasmin, C1r and C1s. Activity is 1000 fold greater than PMSF.

REFERENCES

• Cole, T.C., et al., Biochim. Biophys. Acta , 990 : 254, (1989).