FORSKOLIN

• Catalog No.: 02190669
• CAS Number: 66575-29-9
• M. F.: C22H34O7
• M. W.: 410.50116
• Storage: 0°C, Desiccate

SYNONYMS

• IUPAC name: (3R,4aR,5S,6S,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-dodecahydro-1H-naphtho[2,1-b]pyran-5-yl acetate
• IUPAC Traditional name: (3R,4aR,5S,6S,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-hexahydro-2H-naphtho[2,1-b]pyran-5-yl acetate

DATABASE IDS

• CAS Number: 66575-29-9
• EC Number: 266-410-9

PROPERTIES

• Melting Point: 228-230°C
• RTECS: QL6150000
• Storage Condition: 0°C, Desiccate

DETAILS

Description (English)

From Coleus forskohlii (7β-acetoxy-8,13-epoxy-1a,6β,9a-trihydroxy-labd-14-ene-11-one)
Reported to demonstrate positive inotropic and heart rate-increasing activity at low doses in animals. Also functions as an antihypertensive and vasodilator at higher doses. Activates adenylcyclase in rat liver membranes.

REFERENCES

• H. Metzger and E.Lindner, I.R.C.S. Med. Sci., Biochem., Cardiovascular System Pharm., 9: 99 (1981).