CHAPSO

• Catalog No.: 02190320
• CAS Number: 82473-24-3
• M. F.: C32H58N2O8S
• M. W.: 630.87652
• Storage: Room Temperature (15-30°C)

SYNONYMS

• IUPAC name: 3-[dimethyl({3-[(4R)-4-[(1S,2S,5R,7S,9R,10R,11S,14R,15R,16S)-5,9,16-trihydroxy-2,15-dimethyltetracyclo[8.7.0.0?,?.0??,??]heptadecan-14-yl]pentanamido]propyl})azaniumyl]-2-hydroxypropane-1-sulfonate
• IUPAC Traditional name: 3-[dimethyl({3-[(4R)-4-[(1S,2S,5R,7S,9R,10R,11S,14R,15R,16S)-5,9,16-trihydroxy-2,15-dimethyltetracyclo[8.7.0.0?,?.0??,??]heptadecan-14-yl]pentanamido]propyl})ammonio]-2-hydroxypropane-1-sulfonate
• Synonyms: 3-[(3-Cholamidopropyl)-dimethyl-ammonio]-2-hydroxy-1-propane sulfonate

DATABASE IDS

• CAS Number: 82473-24-3

PROPERTIES

• Melting Point: 184-186°C
• Storage Condition: Room Temperature (15-30°C)

DETAILS

Description (English)

A nondenaturing zwitterionic detergent for solubilizing proteins. It has a more polar head group than CHAPS, giving it greater solubility. CHAPSO has a high Cmc (8mM) and does not denature membrane-bound proteins. It can solubilize the opiate receptor in a state exhibiting reversible binding of opiates.

REFERENCES

• W.F. Simonds, et al., Proc. Nat'l. Acad. Sci. USA , 77 : 4-623 (1980).