BREFELDIN A

• Catalog No.: 02159027
• CAS Number: 20350-15-6
• M. F.: C16H24O4
• M. W.: 280.35936
• Purity: 98%
• Storage: -20°C

SYNONYMS

• IUPAC name: 1,13-dihydroxy-6-methyl-1H,4H,6H,7H,8H,9H,11aH,12H,13H,14H,14aH-cyclopenta[f]oxacyclotridecan-4-one
• IUPAC Traditional name: 1,13-dihydroxy-6-methyl-1H,6H,7H,8H,9H,11aH,12H,13H,14H,14aH-cyclopenta[f]oxacyclotridecan-4-one
• Synonyms: BFA; (-4-Dihydroxy-2-[6-Hydroxy-1-Heptenyl]-4-Cyclopentane Crotonic Acid 8-Lactone

DATABASE IDS

• CAS Number: 20350-15-6

PROPERTIES

• Purity: 98%
• RTECS: GY8410000
• Storage Condition: -20°C

DETAILS

Description (English)

Purity: 98%
Blocks binding of the cytosolic coat protein β-COP and ARF to Golgi membranes mediated by protein G. Also blocks protein transportation into post-Golgi compartments.

REFERENCES

• Donaldson, J.G., et al., Science, 254: 1197 (1991).
• Donaldson, J.G., et al., J. Cell. Biol., 112: 579 (1991).
• Orci, L., et al. Cell, 64: 1183 (1991).
• Lippincott-Schwartz, J., et al., ibid., 60: 821 (1990).