THAPSIGARGIN

• Catalog No.: 02158999
• CAS Number: 67526-95-8
• M. F.: C34H50O12
• M. W.: 650.7536
• Purity: 99%
• Storage: -20°C

SYNONYMS

• IUPAC name: 6-(acetyloxy)-4-(butanoyloxy)-3,3a-dihydroxy-3,6,9-trimethyl-8-[(2-methylbut-2-enoyl)oxy]-2-oxo-2H,3H,3aH,4H,5H,6H,6aH,7H,8H,9bH-azuleno[4,5-b]furan-7-yl octanoate
• IUPAC Traditional name: 6-(acetyloxy)-4-(butanoyloxy)-3,3a-dihydroxy-3,6,9-trimethyl-8-[(2-methylbut-2-enoyl)oxy]-2-oxo-4H,5H,6aH,7H,8H,9bH-azuleno[4,5-b]furan-7-yl octanoate

DATABASE IDS

• CAS Number: 67526-95-8

PROPERTIES

• Purity: 99%
• European Hazard Symbols: Irritant (Xi)
• Risk Statements: R:36/37/38
• Safety Statements: S:20-25-26-37/39
• Storage Condition: -20°C

DETAILS

Description (English)

Purity: 99% Cell permeable sesquiterpene lactone tumor promoter. Inhibits endoplasmic reticulum Ca^2+ -ATPase which induces the release of independent intracellular Ca^2+ .

REFERENCES

• Fujiki, H., et al., Carcinogenesis, 7: 707, (1986).
• Takemura, H., et al., J. Biol. Chem., 264: 12266, (1989).
• Thastrup, O., et al., Proc. Natl. Acad. Sci. USA, 87: 2466, (1990).