MANOALIDE

• Catalog No.: 02158951
• CAS Number: 75088-80-1
• M. F.: C25H36O5
• M. W.: 416.55034
• Purity: ≥95%
• Storage: -20°C

SYNONYMS

• IUPAC name: 5-hydroxy-4-{6-hydroxy-5-[4-methyl-6-(2,6,6-trimethylcyclohex-1-en-1-yl)hex-3-en-1-yl]-3,6-dihydro-2H-pyran-2-yl}-2,5-dihydrofuran-2-one
• IUPAC Traditional name: manoalide

DATABASE IDS

• CAS Number: 75088-80-1

PROPERTIES

• Purity: ≥95%
• Storage Condition: -20°C

DETAILS

Description (English)

From Luffariella variabilis
Purity: >95%
Phospholipase A₂ and C inhibitor. Also blocks the release of arachidonate and inhibits calcium channels.

REFERENCES

• Jacobson, P.B., et al., Biochem. Pharmacol. , 39 : 1557, (1990).
• Wheeler, L.A., et al., J. Biol. Chem. , 262 : 6531, (1987).
• Glaser, K.B. and Jacobs, R.S., ibid. , 36 : 2079, (1987).
• Lombardo, D. and Dennis, E.A., J. Biol. Chem. , 260 : 7234, (1985).
• Mayer, A.M.S., et al., J. Pharm. Exp. Ther. , 244 : 871, (1988).
• Bennertt, C., et al., Pharmacologist , 28 : 538, (1986)