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MANOALIDE

Catalog No. 02158951 Name MP Biomedicals
CAS Number 75088-80-1 Website http://www.mpbio.com
M. F. C25H36O5 Telephone
M. W. 416.55034 Fax
Purity ≥95% Email
Storage -20°C Chembase ID: 105164

SYNONYMS

IUPAC name
5-hydroxy-4-{6-hydroxy-5-[4-methyl-6-(2,6,6-trimethylcyclohex-1-en-1-yl)hex-3-en-1-yl]-3,6-dihydro-2H-pyran-2-yl}-2,5-dihydrofuran-2-one
IUPAC Traditional name
manoalide

DATABASE IDS

CAS Number 75088-80-1

PROPERTIES

Certificate of Analysis Download
Purity ≥95%
MSDS Link Download
Storage Condition -20°C

DETAILS

Description (English)
From Luffariella variabilis
Purity: >95%
Phospholipase A2 and C inhibitor. Also blocks the release of arachidonate and inhibits calcium channels.

REFERENCES

  • Jacobson, P.B., et al., Biochem. Pharmacol. , 39 : 1557, (1990).
  • Wheeler, L.A., et al., J. Biol. Chem. , 262 : 6531, (1987).
  • Glaser, K.B. and Jacobs, R.S., ibid. , 36 : 2079, (1987).
  • Lombardo, D. and Dennis, E.A., J. Biol. Chem. , 260 : 7234, (1985).
  • Mayer, A.M.S., et al., J. Pharm. Exp. Ther. , 244 : 871, (1988).
  • Bennertt, C., et al., Pharmacologist , 28 : 538, (1986)