D-myo-INOSITOL 1,4,5-TRISPHOSPHATE TRIPOTASSIUM SALT

• Catalog No.: 02158354
• CAS Number: 103476-24-0
• M. F.: C6H12K3O15P3
• M. W.: 534.366663
• Storage: -20°C, Store Under Nitrogen

SYNONYMS

• IUPAC name: tripotassium (1R,2R,3S,4R,5R,6S)-2,4-bis(hydrogen phosphonatooxy)-3,5,6-trihydroxycyclohexyl hydrogen phosphate
• IUPAC Traditional name: tripotassium (1R,2R,3S,4R,5R,6S)-2,4-bis(hydrogen phosphonatooxy)-3,5,6-trihydroxycyclohexyl hydrogen phosphate

DATABASE IDS

• CAS Number: 103476-24-0

PROPERTIES

• Storage Condition: -20°C, Store Under Nitrogen

DETAILS

Description (English)

Tripotassium Salt
Ins (1,4,5)P₃
Synthetic
Enantiomerically pure. Greater than 99% pure as per ^1 H and ^31 P NMR
Functions as a second messenger in the release of calcium from intracellular organelles; has been implicated as a mediator of phototransduction in Limulus photoreceptors where it effects changes in ion permeability and sodium ion currents.
Soluble in water.

REFERENCES

• Berridge, M.J. and Irvine, R.F., Nature , 312 : 315, (1984).
• Brown, J.E., et al., Nature , 311 : 160, (1984).
• Grado, C. and Ballou, C.E., J. Biol. Chem. , 236 : 54, (1961).
• Tomlinson, R.V. and Ballou, C.E., J. Biol. Chem. , 236 : 1902, (1961).
• Brockerhoff, H. and Ballou, C.E., J. Biol. Chem. , 236 : 1907, (1961).