N-ACETYL-D-GLUCOSAMINYL-β-(1→4)-N-ACETYLMURAMYL-L-ALANYL-D-ISOGLUTAMINE

• Catalog No.: 02158221
• CAS Number: 70280-03-4
• M. F.: C27H43N5O16
• M. W.: 693.65422
• Purity: 98%
• Storage: -20°C, Desiccate, Protect from light

SYNONYMS

• IUPAC name: (4R)-4-carbamoyl-4-[(2S)-2-[(2R)-2-{[(3R,4R,5S,6R)-3-acetamido-5-{[(2S,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-6-(hydroxymethyl)-2-oxooxan-4-yl]oxy}propanamido]propanamido]butanoic acid
• IUPAC Traditional name: (4R)-4-carbamoyl-4-[(2S)-2-[(2R)-2-{[(3R,4R,5S,6R)-3-acetamido-5-{[(2S,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-6-(hydroxymethyl)-2-oxooxan-4-yl]oxy}propanamido]propanamido]butanoic acid
• Synonyms: GMDP

DATABASE IDS

• CAS Number: 70280-03-4

PROPERTIES

• Purity: 98%
• RTECS: MA2275230
• Storage Condition: -20°C, Desiccate, Protect from light

DETAILS

Description (English)

Purity: 98%
Lyophilized
A novel synthetic analog of bacterial cell wall glycopeptide which acts as a modulator of humoral and cellular immunity reactions. Possesses immunoadjuvant and protective activity against bacterial and viral (including tumorigenic) infections. Differs from well-known muramyl peptides in that it contains GlcNAC attached to muramic acid via the β-(1𔾸) glycosidic bond.
Soluble in H₂ O, EtOH, MeOH, DMF, and physiological saline (1g/ml)

REFERENCES

• Campbell, M.J., et al., J. Immunology , 145 : 1029, (1990).
• Balitsky, K.P., et al., Int. J. Immunopharmacol. , 11 : 429, (1989).