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Fencamfamine

Catalog No. DB01463 Name DrugBank
CAS Number 1209-98-9 Website http://www.ualberta.ca/
M. F. C15H21N Telephone (780) 492-3111
M. W. 215.33394 Fax (780) 492-1071
Purity Email david.wishart@ualberta.ca
Storage Chembase ID: 1262

SYNONYMS

IUPAC name
N-ethyl-3-phenylbicyclo[2.2.1]heptan-2-amine
IUPAC Traditional name
fencamfamine
Brand Name
Glucoenergan
Reactivan
Euvitol
Synonyms
Fencamfamine [inn-french]
Fencamfamina [dcit]
Fencamfamine hydrochloride
Fencamfamin
Fencamfamin hydrochloride
Fencamfaminum [inn-latin]
Fencanfamina [inn-spanish]
2-Ethylamino-3-phenylnorcamphane hydrochloride
2-Ethylamino-3-phenyl-norcamphane hydrochloride
2-Aethylamino-3-phenyl-nor-camphan

DATABASE IDS

PubChem SID 46508161
CAS Number 1209-98-9
PubChem CID 14584

PROPERTIES

Hydrophobicity(logP) 3.20 [SANGSTER (1994)]

DETAILS

Description (English)
Item Information
Drug Groups illicit; approved; withdrawn
Description Fencamfamine (Glucoenergan, Reactivan) is a stimulant which was developed in the 1960s as an appetite suppressant, but was later withdrawn for this application due to problems with dependence and abuse. It is around half the potency of dexamphetamine, and is prescribed at a dose of 10-60mg, although abusers of the drug tend to rapidly develop tolerance and escalate their dose. Reactivan is still rarely used for treating depressive day-time fatigue, lack of concentration and lethargy, particularly in individuals who have chronic medical conditions, as its favourable safety profile makes it the most suitable drug in some cases. [Wikipedia]
Indication For the the treatment of depressive fatigue in convalescence and other debilitated states as well as in the treatment of depressive day-time fatigue, lack of concentration and lethargy.
Pharmacology Fencamfamine increases drive and mental alertness and an elevation of mood and a general feeling of well-being. It is a central nervous system stimulant, which increases locomotor activity.
Toxicity Overdosage is characterised by nausea, agitation and restlessness, dryness of the mouth, dizziness and tremor. In gross overdosage the above symptoms may also be associated with dyspnoea, tachycardia, disorientation and convulsions.
Affected Organisms
Humans and other mammals
References
[Link]
DeLucia R, Planeta CS: Fencamfamine. Gen Pharmacol. 1990;21(2):161-3. [Pubmed]
External Links
Wikipedia

REFERENCES

  • Link
  • DeLucia R, Planeta CS: Fencamfamine. Gen Pharmacol. 1990;21(2):161-3. Pubmed