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ANTIBIOTIC A23187_Molecular_structure_CAS_52665-69-7)
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ANTIBIOTIC A23187

Catalog No. 02152328 Name MP Biomedicals
CAS Number 52665-69-7 Website http://www.mpbio.com
M. F. C29H37N3O6 Telephone
M. W. 523.62058 Fax
Purity Email
Storage -20°C Chembase ID: 103588

SYNONYMS

IUPAC name
5-(methylamino)-2-({3,9,11-trimethyl-8-[1-oxo-1-(1H-pyrrol-2-yl)propan-2-yl]-1,7-dioxaspiro[5.5]undecan-2-yl}methyl)-1,3-benzoxazole-4-carboxylic acid
IUPAC Traditional name
calcimycin
Synonyms
Calcium Ionophore A23187

DATABASE IDS

EC Number 258-084-1
CAS Number 52665-69-7

PROPERTIES

Certificate of Analysis Download
Melting Point 186°C
European Hazard Symbols Irritant Irritant (Xi)
MSDS Link Download
Risk Statements R:36/37/38
RTECS DM4676000
Safety Statements S:20-25-26-37/39
Storage Condition -20°C

DETAILS

Description (English)
Free Acid
White crystalline solid.
Antibiotic A23187 is an antibiotic which demonstrates weak in vitro activity against gram-positive bacteria and fungi. It also has the ability to form stable complexes with divalent cations, increasing their ability to cross biological membranes, thus giving A23187 properties as an ionophore. Its U.V. and fluorescence spectral properties allow this calcium ionophore to be useful as a cytoplasmic free calcium ion probe. A23187 does exhibit toxicity and is a potential health hazard, so caution should be used when handling, in accordance with normal procedures for handling toxic compounds.

REFERENCES