Antipyrine

• Catalog No.: DB01435
• CAS Number: 60-80-0
• M. F.: C11H12N2O
• M. W.: 188.22578

SYNONYMS

• IUPAC name: 1,5-dimethyl-2-phenyl-2,3-dihydro-1H-pyrazol-3-one
• IUPAC Traditional name: antipyrine
• Brand Name: Apirelina; Sedatin; Sedatine; Auralgan
• Synonyms: Pyrazoline; Analgesine; Phenazone; Anodynine; Antipyrinum; Acetasol; Anodynin; Antipirin; Antipyrin; Azophen; Fenazona [inn-spanish]; Fenazone; Phenazon; Azophenum; Fenazon [czech]; Phenozone

DATABASE IDS

• CAS Number: 60-80-0
• PubChem SID: 46505216
• PubChem CID: 2206

PROPERTIES

• Hydrophobicity(logP): 0.38 [HANSCH,C ET AL. (1995)]
• Solubility: 51.9 mg/mL at 25 oC [YALKOWSKY,SH & DANNENFELSER,RM (1992)]

DETAILS

Description (English)

• Drug Groups: approved
• Description: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
• Indication: Antipyrine is an analgesic often used to test effects of other drugs on liver enzymes..
• Pharmacology: Antipyrine is an analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
• Affected Organisms: Humans and other mammals
• External Links: Wikipedia; PDRhealth