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Antipyrine

Catalog No. DB01435 Name DrugBank
CAS Number 60-80-0 Website http://www.ualberta.ca/
M. F. C11H12N2O Telephone (780) 492-3111
M. W. 188.22578 Fax (780) 492-1071
Purity Email david.wishart@ualberta.ca
Storage Chembase ID: 1242

SYNONYMS

IUPAC name
1,5-dimethyl-2-phenyl-2,3-dihydro-1H-pyrazol-3-one
IUPAC Traditional name
antipyrine
Brand Name
Apirelina
Sedatin
Sedatine
Auralgan
Synonyms
Pyrazoline
Analgesine
Phenazone
Anodynine
Antipyrinum
Acetasol
Anodynin
Antipirin
Antipyrin
Azophen
Fenazona [inn-spanish]
Fenazone
Phenazon
Azophenum
Fenazon [czech]
Phenozone

DATABASE IDS

CAS Number 60-80-0
PubChem SID 46505216
PubChem CID 2206

PROPERTIES

Hydrophobicity(logP) 0.38 [HANSCH,C ET AL. (1995)]
Solubility 51.9 mg/mL at 25 oC [YALKOWSKY,SH & DANNENFELSER,RM (1992)]

DETAILS

Description (English)
Item Information
Drug Groups approved
Description An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
Indication Antipyrine is an analgesic often used to test effects of other drugs on liver enzymes..
Pharmacology Antipyrine is an analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
Affected Organisms
Humans and other mammals
External Links
Wikipedia
PDRhealth

REFERENCES