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Oxybenzone

Catalog No. DB01428 Name DrugBank
CAS Number 131-57-7 Website http://www.ualberta.ca/
M. F. C14H12O3 Telephone (780) 492-3111
M. W. 228.24328 Fax (780) 492-1071
Purity Email david.wishart@ualberta.ca
Storage Chembase ID: 1236

SYNONYMS

IUPAC name
2-benzoyl-5-methoxyphenol
IUPAC Traditional name
oxybenzone
Synonyms
4-Methoxy-2-hydroxybenzophenone
Oxibenzona [inn-spanish]
2-Hydroxy-4-methoxybenzophenone
(2-Hydroxy-4-methoxyphenyl)phenylmethanone
4-Methoxy-2-hydroxybenzophenone butyric acid
2-Benzoyl-5-methoxyphenol
Oxybenzonum [inn-latin]

DATABASE IDS

CAS Number 131-57-7
PubChem CID 4632
PubChem SID 46508419

PROPERTIES

Hydrophobicity(logP) 3.79 [CHEM INSPECT TEST INST (1992)]

DETAILS

Description (English)
Item Information
Drug Groups approved
Description Oxybenzone is an organic compound used in sunscreens. It is a derivative of benzophenone. It forms colorless crystals that are readily soluble in most organic solvents. It is used as an ingredient in sunscreen and other cosmetics because it absorbs UV-A ultraviolet rays.
Indication Used as an ingredient in sunscreen and other cosmetics.
Pharmacology Oxybenzone is an organic compound used in sunscreens. It is a derivative of benzophenone.
Affected Organisms
Humans and other mammals
Elimination In vivo studies show oxybenzone is abosorbed transdermally (through the skin) and is excreted in the urine.
References
Gonzalez H, Farbrot A, Larko O, Wennberg AM: Percutaneous absorption of the sunscreen benzophenone-3 after repeated whole-body applications, with and without ultraviolet irradiation. Br J Dermatol. 2006 Feb;154(2):337-40. [Pubmed]
External Links
Wikipedia

REFERENCES

  • Gonzalez H, Farbrot A, Larko O, Wennberg AM: Percutaneous absorption of the sunscreen benzophenone-3 after repeated whole-body applications, with and without ultraviolet irradiation. Br J Dermatol. 2006 Feb;154(2):337-40. Pubmed