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Oxybenzone

Catalog No. DB01428 Name DrugBank
CAS Number 131-57-7 Website http://www.ualberta.ca/
M. F. C14H12O3 Telephone (780) 492-3111
M. W. 228.24328 Fax (780) 492-1071
Purity Email david.wishart@ualberta.ca
Storage Chembase ID: 1236

SYNONYMS

IUPAC name
2-benzoyl-5-methoxyphenol
IUPAC Traditional name
oxybenzone
Synonyms
4-Methoxy-2-hydroxybenzophenone
Oxibenzona [inn-spanish]
2-Hydroxy-4-methoxybenzophenone
(2-Hydroxy-4-methoxyphenyl)phenylmethanone
4-Methoxy-2-hydroxybenzophenone butyric acid
2-Benzoyl-5-methoxyphenol
Oxybenzonum [inn-latin]

DATABASE IDS

CAS Number 131-57-7
PubChem CID 4632
PubChem SID 46508419

PROPERTIES

Hydrophobicity(logP) 3.79 [CHEM INSPECT TEST INST (1992)]

DETAILS

Description (English)
Item Information
Drug Groups approved
Description Oxybenzone is an organic compound used in sunscreens. It is a derivative of benzophenone. It forms colorless crystals that are readily soluble in most organic solvents. It is used as an ingredient in sunscreen and other cosmetics because it absorbs UV-A ultraviolet rays.
Indication Used as an ingredient in sunscreen and other cosmetics.
Pharmacology Oxybenzone is an organic compound used in sunscreens. It is a derivative of benzophenone.
Affected Organisms
• Humans and other mammals
Elimination In vivo studies show oxybenzone is abosorbed transdermally (through the skin) and is excreted in the urine.
References
• Gonzalez H, Farbrot A, Larko O, Wennberg AM: Percutaneous absorption of the sunscreen benzophenone-3 after repeated whole-body applications, with and without ultraviolet irradiation. Br J Dermatol. 2006 Feb;154(2):337-40. [Pubmed]
External Links
• Wikipedia

REFERENCES

  • Gonzalez H, Farbrot A, Larko O, Wennberg AM: Percutaneous absorption of the sunscreen benzophenone-3 after repeated whole-body applications, with and without ultraviolet irradiation. Br J Dermatol. 2006 Feb;154(2):337-40. Pubmed