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β-ALA-HIS

Catalog No. 02100936 Name MP Biomedicals
CAS Number 305-84-0 Website http://www.mpbio.com
M. F. C9H14N4O3 Telephone
M. W. 226.23246 Fax
Purity ~99% Email
Storage 0°C Chembase ID: 102276

SYNONYMS

IUPAC name
2-(3-aminopropanamido)-3-(1H-imidazol-4-yl)propanoic acid
IUPAC Traditional name
carnosine
Synonyms
L-Carnosine
β-Alanyl-L-histidine

DATABASE IDS

EC Number 206-169-9
CAS Number 305-84-0

PROPERTIES

Certificate of Analysis Download
Purity ~99%
MSDS Link Download
RTECS MS3080000
Storage Condition 0°C

DETAILS

Description (English)
Dipeptide with potent antioxidant and antiglycation activity; blocks nonenzymatic glycosylation and protein cross-linking induced by reactive aldehydes.
L-Carosine is a dipeptide found at millimolar concentration in brain, muscle and the lens of the eye. In model systems it is a potent antioxidant that scavenges oxygen free radicals and transition metal ions. It blocks protein-protein and protein-DNA cross-links induced by hypochlorite anions and toxic aldehydes such as acetaldehyde, formaldehyde, and malondialdehyde, the primary product of lipid peroxidation. It also inhibits nonenzymatic protein glycation induced by aldose and ketose reducing sugars and inhibits the formation of toxic advanced glycation end products (AGE). These activities make it of interest in studies of aging, atherosclerosis, Alzheimer's disease, and the secondary effects of diabetes.
Crystalline
Purity: Approx. 99%

REFERENCES