Alizapride

• Catalog No.: DB01425
• CAS Number: 59338-93-1
• M. F.: C16H21N5O2
• M. W.: 315.37024

SYNONYMS

• IUPAC name: 6-methoxy-N-{[1-(prop-2-en-1-yl)pyrrolidin-2-yl]methyl}-2H-1,2,3-benzotriazole-5-carboxamide
• IUPAC Traditional name: alizapride
• Brand Name: Liticum; Limican
• Synonyms: Alizaprida [inn-spanish]; Alizapridum [inn-latin]

DATABASE IDS

• PubChem SID: 46505555
• CAS Number: 59338-93-1
• PubChem CID: 43008

PROPERTIES

• Hydrophobicity(logP): 1.79 [MANNHOLD,R ET AL. (1990)]

DETAILS

Description (English)

• Drug Groups: approved
• Description: Alizapride is a dopamine antagonist with prokinetic and antiemetic effects used in the treatment of nausea and vomiting, including postoperative nausea and vomiting.
• Indication: Alizapride is used in the treatment of nausea and vomiting, including postoperative nausea and vomiting.
• Pharmacology: Alizapride is a dopamine antagonist.
• Half Life: 3 hours
• Elimination: renal
• References: Bleiberg H, Gerard B, Dalesio O, Crespeigne N, Rozencweig M: Activity of a new antiemetic agent: alizapride. A randomized double-blind crossover controlled trial. Cancer Chemother Pharmacol. 1988;22(4):316-20. [Pubmed]
• External Links: Wikipedia

REFERENCES

• Bleiberg H, Gerard B, Dalesio O, Crespeigne N, Rozencweig M: Activity of a new antiemetic agent: alizapride. A randomized double-blind crossover controlled trial. Cancer Chemother Pharmacol. 1988;22(4):316-20. Pubmed