| Item |
Information |
|
Drug Groups
|
approved |
|
Description
|
Bambuterol is a long acting beta-adrenoceptor agonist used in the treatment of asthma. It is a prodrug of terbutaline. |
| Indication |
For the prevention and reversal of bronchospasm in patients 12 years of age and older with asthma and reversible bronchospasm associated with bronchitis and emphysema. |
| Pharmacology |
Bambuterol is a long acting beta2-adrenoceptor agonist used in the treatment of asthma. It is a prodrug of terbutaline. Bambuterol causes smooth muscle relaxation, resulting in dilation of bronchial passages. |
| Affected Organisms |
| • |
Humans and other mammals |
|
| Biotransformation |
Hepatic, extensive. Further metabolized to terbutaline by plasma cholinesterase. |
| Absorption |
Bioavailability is 20% following oral administration. |
| Half Life |
13 hours for bambuterol and 21 hours for the primary active metabolite terbutaline. |
| External Links |
|