Butethal

• Catalog No.: DB01353
• CAS Number: 77-28-1
• M. F.: C10H16N2O3
• M. W.: 212.24564

SYNONYMS

• IUPAC name: 5-butyl-5-ethyl-1,3-diazinane-2,4,6-trione
• IUPAC Traditional name: butethal
• Brand Name: Etoval; Neonal; Sonerile; Hyperbutal; Longanoct; Meonal; Soneryl; Monodorm; Budorm
• Synonyms: Butobarbitalum; 5-Ethyl-5-N-butylbarbituric acid; Butobarbital; 5-Butyl-5-ethyl-2,4,6(1H,3H,5H)-pyrimidinetrione; 5-Butyl-5-ethylbarbituric acid; Butobarbitone; Butabarbitol; Butobarbitural; Butyl,5-ethylbarbituric acid; 5-Ethyl-5-butylbarbituric acid

DATABASE IDS

• CAS Number: 77-28-1
• PubChem CID: 6473
• PubChem SID: 46508397

PROPERTIES

• Hydrophobicity(logP): 1.73 [HANSCH,C ET AL. (1995)]
• Solubility: 4.88 mg/mL at 25 oC [YALKOWSKY,SH & DANNENFELSER,RM (1992)]

DETAILS

Description (English)

• Drug Groups: illicit; approved
• Description: Butethal is a sedative and a hypnotic drug.
• Indication: For the treatment of insomnia.
• Pharmacology: Butethal (also known as butobarbitone and butobarbital) belongs to a group of medicines called the barbiturates. It is thought to act on receptors in the brain (GABA receptors) causing the release of the chemical GABA. This chemical inhibits certain areas of the brain resulting in sleepiness.
• Toxicity: Signs of overdose include confusion (severe), decrease in or loss of reflexes, drowsiness (severe), fever, irritability (continuing), low body temperature, poor judgment, shortness of breath or slow or troubled breathing, slow heartbeat, slurred speech, staggering, trouble in sleeping, unusual movements of the eyes, weakness (severe).
• Affected Organisms: Humans and other mammals
• Biotransformation: Hepatic.
• Absorption: Rapidly absorbed following oral administration.
• Half Life: 37 hours
• External Links: Wikipedia