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Polystyrene sulfonate

Catalog No. DB01344 Name DrugBank
CAS Number 28210-41-5 Website http://www.ualberta.ca/
M. F. C8H7O3S- Telephone (780) 492-3111
M. W. 183.20438 Fax (780) 492-1071
Purity Email david.wishart@ualberta.ca
Storage Chembase ID: 1174

SYNONYMS

Brand Name
Kayexalate
Kionex
Synonyms
Sodium polystyrene sulfonic acid
SPS
Polystyrene sulfonic acid
Sodium polystyrene sulfonate

DATABASE IDS

CAS Number 28210-41-5
PubChem SID 46507832
PubChem CID 169893

PROPERTIES

DETAILS

Description (English)
Item Information
Drug Groups approved
Description Sodium polystyrene sulfonate is a medication used to treat abnormally high potassium levels. It may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines. It is also an effective topical microbicide and spermicide, inhibiting the genital transfection of, among others, HIV. [Wikipedia]
Indication Used to treat abnormally high potassium levels.
Pharmacology Polystyrene sulfonate affects the exchange of sodium and potassium in the body. Polystyrene sulfonate is used to treat high levels of potassium in the blood, also called hyperkalemia. It is a potassium-binding ion-exchange resin that can be administered orally (25 grams in 20% sorbitol) or rectally (50 grams in 20% sorbitol).
Toxicity Overdose symptoms may include confusion, irritability, trouble thinking or concentrating, muscle weakness, or trouble breathing.
Affected Organisms
Humans and other mammals
Biotransformation none
Absorption Not absorbed following oral administration.
Half Life none
Elimination Feces.
External Links
Wikipedia

REFERENCES