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Josamycin

Catalog No. DB01321 Name DrugBank
CAS Number 16846-24-5 Website http://www.ualberta.ca/
M. F. C42H69NO15 Telephone (780) 492-3111
M. W. 827.99496 Fax (780) 492-1071
Purity Email david.wishart@ualberta.ca
Storage Chembase ID: 1156

SYNONYMS

IUPAC name
(2S,3S,4R,6S)-6-{[(2R,3S,4R,5R,6S)-6-{[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-4-(acetyloxy)-10-hydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-6-yl]oxy}-4-(dimethylamino)-5-hydroxy-2-methyloxan-3-yl]oxy}-4-hydroxy-2,4-dimethyloxan-3-yl 3-methylbutanoate
IUPAC Traditional name
josamycin
Brand Name
Turimycin A5
Josacine
Kitasamycin A3
Synonyms
Josamicina [inn-spanish]
Leucomycin V, 3-acetate 4B-(3-methylbutanoate)
Leucomycin A3
JM
Antibiotic yl-704 A3
Josamycine [inn-french]
Josamycinum [inn-latin]
Leucomycin V, 3-acetate 4(sup B)-(3-methylbutanoate)
Leucomycin V, 3-acetate 4(sup beta)-(3-methylbutanoate)

DATABASE IDS

PubChem CID 5282165
PubChem SID 46505431
CAS Number 16846-24-5

PROPERTIES

DETAILS

Description (English)
Item Information
Drug Groups approved
Description A macrolide antibiotic from Streptomyces narbonensis. The drug has antimicrobial activity against a wide spectrum of pathogens. [PubChem]
Indication For the treatment of bacterial infections.
Pharmacology Josamycin is a macrolide antibiotic from Streptomyces narbonensis. The drug has antimicrobial activity against a wide spectrum of pathogens.
Affected Organisms
Enteric bacteria and other eubacteria
References
Przybylski P, Pyta K, Stefanska J, Brzezinski B, Bartl F: Structure elucidation, complete NMR assignment and PM5 theoretical studies of new hydroxy-aminoalkyl-alpha,beta-unsaturated derivatives of the macrolide antibiotic josamycin. Magn Reson Chem. 2010 Apr;48(4):286-96. [Pubmed]
External Links
Wikipedia

REFERENCES

  • Przybylski P, Pyta K, Stefanska J, Brzezinski B, Bartl F: Structure elucidation, complete NMR assignment and PM5 theoretical studies of new hydroxy-aminoalkyl-alpha,beta-unsaturated derivatives of the macrolide antibiotic josamycin. Magn Reson Chem. 2010 Apr;48(4):286-96. Pubmed