Home > Compound List > Product Information
Oxtriphylline_Molecular_structure_CAS_4499-40-5)
Click picture or here to close

Oxtriphylline

Catalog No. DB01303 Name DrugBank
CAS Number 4499-40-5 Website http://www.ualberta.ca/
M. F. C12H21N5O3 Telephone (780) 492-3111
M. W. 283.32684 Fax (780) 492-1071
Purity Email david.wishart@ualberta.ca
Storage Chembase ID: 1153

SYNONYMS

IUPAC name
(2-hydroxyethyl)trimethylazanium; 1,3-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-7-ide
IUPAC Traditional name
1,3-dimethyl-2,6-dioxo-7H-purin-7-ide; choline
Brand Name
Theocolin
Choledyl
Synonyms
Choline theophylline

DATABASE IDS

PubChem CID 656652
PubChem SID 46507376
CAS Number 4499-40-5

PROPERTIES

DETAILS

Description (English)
Item Information
Drug Groups approved
Description Oxtriphylline is a cough medicine derived from xanthine and similar to theophylline, that acts as a bronchodilator to open up airways in the lung. It antagonizes adenosine receptors and promotes relaxation of airway smooth muscles. It is also thought to inhibit phosphodiesterases leading to higher levels of cAMP and increased bronchodilation.
Indication Used to treat the symptoms of asthma, bronchitis, and emphysema.
Pharmacology Oxtriphylline is a bronchodilator. Oxtriphylline works in several ways: it relaxes muscles in your lungs and chest to allow more air in, decreases the sensitivity of your lungs to allergens and other substances that cause inflammation, and increases the contractions of your diaphragm to draw more air into the lungs.
Toxicity Symptoms of toxicity include abdominal pain (continuing or severe), confusion or change in behavior, convulsions (seizures), dark or bloody vomit, diarrhea, dizziness or lightheadedness, fast and/or irregular heartbeat, nervousness or restlessness (continuing), and trembling (continuing).
Affected Organisms
Humans and other mammals
External Links
Wikipedia
Drugs.com

REFERENCES