Home > Compound List > Product Information
Dihydroergotoxine_Molecular_structure_CAS_11032-41-0)
Click picture or here to close

Dihydroergotoxine

Catalog No. DB01287 Name DrugBank
CAS Number 11032-41-0 Website http://www.ualberta.ca/
M. F. C34H41N5O8S Telephone (780) 492-3111
M. W. 679.78304 Fax (780) 492-1071
Purity Email david.wishart@ualberta.ca
Storage Chembase ID: 1142

SYNONYMS

IUPAC name
(4R,7R)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.0^{2,6}]dodecan-4-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),9,12,14-tetraene-4-carboxamide; methanesulfonic acid
IUPAC Traditional name
(4R,7R)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.0^{2,6}]dodecan-4-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),9,12,14-tetraene-4-carboxamide mesylate

DATABASE IDS

PubChem SID 46505136
PubChem CID 6420006
CAS Number 11032-41-0

PROPERTIES

DETAILS

Description (English)
Item Information
Drug Groups approved
Description Dihydroergotoxine is a cerebral vasodilator. Dihydroergotoxine is a mixture of three different ergotamantriones: dihydroergocornine, dihydroergocristine, and dihydroergocryptine. It has been proposed to be a neuroprotective agent. The mechanism of its therapeutic actions is not clear.
Indication For potential use in the treatment of Alzheimer's disease.
Pharmacology The drug may compensate for neurotransmitter deficits and can in different circumstances, compensate for hyperactivity in the same neurotransmitter pathways. The drug can counteract and prevent disturbances between monoaminergic and other transmitter systems in the CNS.

REFERENCES