Desonide

• Catalog No.: DB01260
• CAS Number: 638-94-8
• M. F.: C24H32O6
• M. W.: 416.50728

SYNONYMS

• IUPAC name: (1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosa-14,17-dien-16-one
• IUPAC Traditional name: desonide
• Brand Name: Desocort; Tridesilon; Desilux; Desowen

DATABASE IDS

• CAS Number: 638-94-8
• PubChem SID: 46506186
• PubChem CID: 5311066

PROPERTIES

• Hydrophobicity(logP): 1.4
• Solubility: Practically insoluble

DETAILS

Description (English)

• Drug Groups: approved; investigational
• Description: A nonfluorinated corticosteroid anti-inflammatory agent used topically for dermatoses. [PubChem]
• Indication: For the relief of the inflammatory and pruritic manifestations of corticosteroid responsive dermatose.
• Pharmacology: Desonide is a synthetic nonfluorinated corticosteroid for topical dermatologic use. The corticosteroids constitute a class of primarily synthetic steroids used topically as anti-inflammatory and antipruritic agents.
• Affected Organisms: Humans and other mammals
• Absorption: Topical corticosteroids can be absorbed from normal intact skin, inflammation and/or other disease processes in the skin may increase percutaneous absorption.
• External Links: Wikipedia; RxList; PDRhealth; Drugs.com