Gadodiamide

• Catalog No.: DB00225
• CAS Number: 122795-43-1
• M. F.: C16H28GdN5O9
• M. W.: 591.67162

SYNONYMS

• IUPAC name: gadolinium(3+) ion 2-[bis({2-[(carboxylatomethyl)[(methylcarbamoyl)methyl]amino]ethyl})amino]acetate hydrate
• IUPAC Traditional name: gadolinium(3+) 2-[bis({2-[(carboxylatomethyl)[(methylcarbamoyl)methyl]amino]ethyl})amino]acetate hydrate
• Brand Name: Omniscan
• Synonyms: Gadodiamide hydrate

DATABASE IDS

• CAS Number: 122795-43-1
• PubChem SID: 46504789
• PubChem CID: 60754

DETAILS

Description (English)

• Drug Groups: approved
• Description: Gadodiamide is a gadolinium based contrast agent used in MR imaging procedures to assist in the visualization of blood vessels. It is commonly marketed under the trade name Omniscan. [Wikipedia]
• Indication: For intravenous use in MRI to visualize lesions with abnormal vascularity (or those thought to cause abnormalities in the blood-brain barrier) in the brain (intracranial lesions), spine, and associated tissues.
• Affected Organisms: Humans and other mammals
• Biotransformation: There is no detectable biotransformation or decomposition of gadodiamide.
• Half Life: Two-compartment model with mean distribution and elimination half-lives (reported as mean ± SD) of 3.7 ± 2.7 minutes and 77.8 ± 16 minutes, respectively.
• Elimination: Gadodiamide is eliminated primarily in the urine.
• Distribution: * 200 ± 61 mL/kg
• Clearance: * Renal cl=1.7 mL/min/kg; * Plasma cl=1.8 mL/min/kg
• External Links: Wikipedia; RxList