Isoetharine

• Catalog No.: DB00221
• CAS Number: 530-08-5
• M. F.: C13H21NO3
• M. W.: 239.31074

SYNONYMS

• IUPAC name: 4-{1-hydroxy-2-[(propan-2-yl)amino]butyl}benzene-1,2-diol
• IUPAC Traditional name: isoetarine
• Brand Name: Isoetarin; Beta-2; Dey-Lute Isoetharine; Etyprenaline; Bronkometer; Bronkosol; Dilabron; Isoetarine; Isoetharine HCl S/F; Neoisuprel
• Synonyms: Isoetharine Hcl; Isoetarinum [INN-Latin]; Isoetarina [INN-Spanish]; Isoetharine mesylate

DATABASE IDS

• PubChem CID: 3762
• PubChem SID: 46505384
• CAS Number: 530-08-5

PROPERTIES

• Hydrophobicity(logP): 2.2
• Solubility: Appreciable

DETAILS

Description (English)

• Drug Groups: approved
• Description: Isoetharine is a selective adrenergic beta-2 agonist used as fast acting bronchodilator for emphysema, bronchitis and asthma. [PubChem]
• Indication: For the treatment of asthma, wheezing, and chronic asthmatic bronchitis.
• Pharmacology: Isoetharine is a relatively selective beta2-adrenergic bronchodilator. Isoetharine is indicated for the relief of bronchospasm associated with chronic obstructive pulmonary disease. Adrenergic bronchodilators are breathed in through the mouth to open up the bronchial tubes (air passages) of the lungs.
• Toxicity: Signs of overdose include tachycardia, palpitations, nausea, headache, and epinephrine-like side effects.
• Affected Organisms: Humans and other mammals
• References: Emerman CL, Cydulka RK, Effron D, Lukens TW, Gershman H, Boehm SP: A randomized, controlled comparison of isoetharine and albuterol in the treatment of acute asthma. Ann Emerg Med. 1991 Oct;20(10):1090-3. [Pubmed]
• External Links: Wikipedia; Drugs.com

REFERENCES

• Emerman CL, Cydulka RK, Effron D, Lukens TW, Gershman H, Boehm SP: A randomized, controlled comparison of isoetharine and albuterol in the treatment of acute asthma. Ann Emerg Med. 1991 Oct;20(10):1090-3. Pubmed