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Candicidin

Catalog No. DB01152 Name DrugBank
CAS Number 1403-17-4 Website http://www.ualberta.ca/
M. F. C59H84N2O18 Telephone (780) 492-3111
M. W. 1109.30086 Fax (780) 492-1071
Purity Email david.wishart@ualberta.ca
Storage Chembase ID: 1023

SYNONYMS

IUPAC name
(19Z,21Z,23Z,25Z,27Z,29Z,31Z)-33-{[(3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy}-17-[7-(4-aminophenyl)-5-hydroxy-4-methyl-7-oxoheptan-2-yl]-1,3,5,7,37-pentahydroxy-18-methyl-9,13,15-trioxo-16,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid
IUPAC Traditional name
candicidin
Brand Name
Vanobid
FR-008-III
Candicidin A
Candicidin D

DATABASE IDS

PubChem SID 46504812
CAS Number 1403-17-4
PubChem CID 441142

PROPERTIES

Hydrophobicity(logP) 1.7

DETAILS

Description (English)
Item Information
Drug Groups approved
Description Candicidin is an antibiotic obtained from a streptomyces (Streptomyces griseus) and active against some fungi of the genus Candida (C. albicans). Candicidin is administered intravaginally in the treatment of vulvovaginal candidiasis.
Indication Used in the topical treatment of vulvovaginal candidiasis.
Pharmacology Candicidin is a polyene antifungal antibiotic produced by a strain of Streptomyces griseus. It is especially effective against Candida albicans (more effective than amphotericin B), and is administered intravaginally in the treatment of vulvovaginal candidiasis.
Affected Organisms
Various Fungus Species
External Links
Wikipedia

REFERENCES