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Pyridoxal Phosphate

Catalog No. DB00114 Name DrugBank
CAS Number 54-47-7 Website http://www.ualberta.ca/
M. F. C8H10NO6P Telephone (780) 492-3111
M. W. 247.141861 Fax (780) 492-1071
Purity Email david.wishart@ualberta.ca
Storage Chembase ID: 1

SYNONYMS

IUPAC name
[(4-formyl-5-hydroxy-6-methylpyridin-3-yl)methoxy]phosphonic acid
IUPAC Traditional name
pyridoxal phosphate
Brand Name
Hairoxal
Hiadelon
Himitan
Vitazechs
Biosechs
Pidopidon
Synonyms
PLP
Pyridoxal 5'-phosphate
Pyridoxal 5-phosphate
Pyridoxal-P
Pyridoxal P
Vitamin B6
Pyridoxal-5P
Codecarboxylase
Pyromijin

DATABASE IDS

CAS Number 54-47-7
PubChem CID 1051
PubChem SID 46506428

PROPERTIES

Hydrophobicity(logP) -1.2
Solubility Appreciable

DETAILS

Description (English)
Item Information
Drug Groups nutraceutical
Description This is the active form of vitamin B6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (pyridoxamine). [PubChem]
Indication For nutritional supplementation and for treating dietary shortage or imbalance.
Pharmacology The two major forms of vitamin B6 are pyridoxine and pyridoxamine. In the liver they are converted to pyridoxal phosphate (PLP) which is a cofactor in many reactions of amino acid metabolism. PLP also is necessary for the enzymatic reaction governing the release of glucose from glycogen. Pyroluria is one potential cause of vitamin B6 deficiency.
Affected Organisms
Humans and other mammals
External Links
Wikipedia
PDRhealth

REFERENCES