sodium fluoride

• ChemBase ID: 99026
• Molecular Formular: FNa
• Molecular Mass: 41.9881732
• Monoisotopic Mass: 41.9881725
• SMILES: [Na+].[F-]
• Canonical SMILES: [F-].[Na+]
• InChI: InChI=1S/FH.Na/h1H;/q;+1/p-1
• InChIKey: PUZPDOWCWNUUKD-UHFFFAOYSA-M

NAMES AND DATABASE IDS

Names

• IUPAC name: sodium fluoride
• IUPAC Traditional name: sodium fluoride; potassium fluoride
• Synonyms: Sodium fluoride 99%; Sodium fluoride 99.99%; Natrii fluoridum; Sodium fluoride solution; Florocid; Sodium fluoride; Fluoride, Ion chromatography standard solution, Specpure®, F? 1000 g/ml; Fluoride ion solution for ISE; Sodium fluoride solution; Fluoride, certified anion standard solution; Additive Screening Solution 19/Fluka kit no 78374; Sodium fluoride 0.5 M solution; Fluoride standard solution; SODIUM FLUORIDE ACS REAGENT GRADE; Sodium fluoride; Sodium fluoride, ACS; Sodium fluoride, Optical Grade; Sodium fluoride, Puratronic®; 氟化钠; 氟化钠 溶液; 氟离子, 离子色谱标准溶液, Specpure®, 氟离子 1000μg/ml; 氟离子标准溶液; 氟化钠 溶液; 氟离子，经认证的阴离子标准溶液 溶液; Fluoride standard solution; 氟化钠; 氟化钠, ACS; 氟化钠, 光学级; 氟化钠, Puratronic®

Database IDs

• CAS Number: 7681-49-4
• EC Number: 231-667-8
• MDL Number: MFCD00003524; MFCD00144315
• Merck Index: 148618
• PubChem SID: 24851998; 24886219; 24887541; 24899482; 162085328; 24852884; 24899503; 24858161; 24899723; 24870675; 24886216; 24868529; 24885200; 24858878; 24845145; 24861071; 24899770; 24889580
• PubChem CID: 5235
• CHEBI ID: 28741
• ATC CODE: A01AA01; A12CD01; V09IX06
• CHEMBL: 1528
• Chemspider ID: 5045
• KEGG ID: C08142
• Unique Ingredient Identifier: 8ZYQ1474W7
• Wikipedia Title: Sodium_fluoride

CALCULATED PROPERTIES

• Acid pKa: 3.17
• H Acceptors: 0
• H Donor: 0
• LogD (pH = 5.5): 0.3684526
• LogD (pH = 7.4): 0.36924794
• Log P: 0.14883864
• Molar Refractivity: 0.8725 cm^3
• Polarizability: 0.45069772 Å^3
• Polar Surface Area: 0.0 Å^2
• Rotatable Bonds: 0
• Lipinski's Rule of Five: true

PROPERTIES

Physical Property

• Solubility: 36.4 (0 °C); 40.4 (20 °C); 50.5 (100 °C) g/L in water; ethanol: insoluble; H2O: soluble0.5 M at 20 °C, clear, colorless; H2O: soluble1 M, clear, colorless; soluble in HF ; insoluble in alcohol; Soluble in water. Insoluble in alcohol
• Apperance: Broken Crystals; Liquid; powder; Powder; White solid
• Melting Point: 988°C; 993 °C(lit.); 993°C; 993°C; ca. 1000 °C
• Boiling Point: 1704 °C/1 atm(lit.); 1704°C; 1704°C; 1705 °C
• Flash Point: Non-flammable
• Density: 1.005 g/mL at 25 °C(lit.); 1.02 g/mL at 20 °C; 1.035-1.040 g/mL at 20 °C; 2.558 g/cm^3; 2.78; 2.780; 2.8 g/cm^3 at 20 °C
• Refractive Index: 1.336; n20/D 1.3252(lit.)
• Vapor Pressure: 1 mm Hg at 1077 °C; 1 mmHg @ 1077 C°; 1.4 mmHg ( 0 °C)
• Absorption Wavelength: λ: 260 nm Amax: 0.01; λ: 280 nm Amax: 0.01
• Odor: odorless
• pH: 7.0-10.0 (25 °C, 0.5 M in H2O)

Safety Information

• Storage Condition: Room Temperature (15-30°C)
• Storage Warning: Hygroscopic; Toxic/Irritant/Moisture Sensitive/Store under Argon
• RTECS: WB0350000
• European Hazard Symbols: Toxic (T); T-Toxic; ; Xi-Irritant; Harmful (Xn)
• UN Number: 1690; UN1690
• German water hazard class: 1; nwg
• Hazard Class: 6.1
• Packing Group: 3; III
• Australian Hazchem: 2Z
• Risk Statements: 22-32; 25-32-36/38; 32; R:25-32-36/38; R25, R32, R36/38
• Safety Statements: 22-36-45; S:22-36-45; S1/2, S22, S36, S45
• EU Classification: T2
• EU Hazard Identification Number: 6.1B
• Emergency Response Guidebook(ERG) Number: 154
• TSCA Listed: 是
• EU Index: 009-004-00-7
• GHS Pictograms: GHS06
• GHS Signal Word: Danger
• NFPA704:
  

  0

  3

  0
• LD50: 52–200 mg/kg (oral in rats, mice, rabbits)
• GHS Hazard statements: H300-H315-H319; H301-H315-H319
• GHS Precautionary statements: P280-P301+P310-P305+P351+P338-P302+P352-P405-P501A; P301 + P310-P305 + P351 + P338
• Personal Protective Equipment: Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter; Eyeshields, Faceshields, Gloves; Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges; Eyeshields, Gloves; Eyeshields, Gloves, half-mask respirator (US), multi-purpose combination respirator cartridge (US)
• RID/ADR: UN 1690 6.1/PG 3
• Supplemental Hazard Statements: Contact with acids liberates very toxic gas.
• Storage Temperature: 2-8°C

Product Information

• Purity: ≥99%; ≥97.0%; ≥98%; ≥98.0% (F); ≥99%; ≥99.0%; ≥99.0% (F); 98.5-100.5% (calc. to the dried substance); 99%; 99% min; 99.99% (metals basis); 99.99% trace metals basis; 99.995% (metals basis excluding K), K ≈60ppm
• Concentration: 0.1 M F-; 1 g/L; 1 mg/mL F-; 1000 mg/kg F-; 40 g/L
• Grade: ACS; ACS reagent; analytical standard (for ion-selective electrodes); anhydrous; for ion chromatography; JIS special grade; Ph Eur; puriss.; puriss. p.a.; purum p.a.; REAGENT; SAJ first grade; technical
• Suitability: complies for appearance of solution; meets USP testing specifications; suitable for insect cell culture
• Impurities: ≤0.0005% Phosphorus (P); ≤0.001% heavy metals (as Pb); ≤0.002% heavy metals (as Pb); ≤0.01 meq/g Titr. base; ≤0.01 meq/g Titratable base; ≤0.01% heavy metals (as Pb); ≤0.02% Insoluble matter; ≤0.02% insolubles; ≤0.03 meq/g Titr. acid; ≤0.03 meq/g Titratable acid; ≤0.04% free alkali (as NaOH); ≤0.05% free acid (as HF); ≤0.1% free alkali (as NaOH); ≤0.1% Insoluble matter; ≤0.1% sodium fluorosilicate; ≤0.1% Sodium fluosilicate (Na2SiF6); ≤0.1% sodium hexafluorosilicate (Na2SiF6); ≤0.2% free acid (as HF); ≤0.2% sodium hexafluorosilicate (Na2SiF6); ≤1% sodium hexafluorosilicate (Na2SiF6); acidity or alkalinity, complies; insoluble matter, passes filter test; organic volatile impurities, complies (GC); residual solvents, complies
• Cation Traces: Al: ≤0.001%; Al: ≤5 mg/kg; As: ≤0.5 mg/kg; Ba: ≤10 mg/kg; Bi: ≤5 mg/kg; Ca: ≤0.0005%; Ca: ≤10 mg/kg; Ca: ≤50 mg/kg; Cd: ≤5 mg/kg; Cd: ≤50 mg/kg; Co: ≤5 mg/kg; Co: ≤50 mg/kg; Cr: ≤5 mg/kg; Cu: ≤0.0005%; Cu: ≤5 mg/kg; Cu: ≤50 mg/kg; Fe: ≤0.003%; Fe: ≤10 mg/kg; Fe: ≤200 mg/kg; Fe: ≤50 mg/kg; heavy metals (as Pb): ≤0.003%; K: ≤0.005%; K: ≤0.02%; K: ≤100 mg/kg; K: ≤200 mg/kg; K: ≤2000 mg/kg; Li: ≤5 mg/kg; Mg: ≤0.0005%; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; NH4+: ≤0.1%; Ni: ≤5 mg/kg; Ni: ≤50 mg/kg; Pb: ≤0.001%; Pb: ≤5 mg/kg; Pb: ≤50 mg/kg; Sr: ≤5 mg/kg; Zn: ≤0.0005%; Zn: ≤5 mg/kg; Zn: ≤50 mg/kg
• Antion Traces: chloride (Cl-): ≤0.005%; chloride (Cl-): ≤10 mg/kg; chloride (Cl-): ≤100 mg/kg; chloride (Cl-): ≤50 mg/kg; hexafluorosilicate (SiF62-): ≤1000 mg/kg; sulfate (SO42-): ≤0.03%; sulfate (SO42-): ≤100 mg/kg; sulfate (SO42-): ≤200 mg/kg; sulfate (SO42-): ≤5000 mg/kg; sulfite (SO32-): ≤0.005%; sulfite (SO32-): ≤50 mg/kg
• Clinical: for in vitro diagnostic use
• Shelf Life: (Expiry date on the label.); (limited shelf life, expiry date on the label)
• Loss on Drying: ≤0.1% loss on drying, 150 °C; ≤0.2% loss on drying, 150 °C; ≤0.3% loss on drying; ≤0.3% loss on drying, 150°C; ≤0.5% loss on drying, 150 °C
• Quality Level: IVD
• Quality: certified by BAM, according to ISO 17025; meets analytical specification of Ph. Eur., BP, USP; volumetric
• λ: 0.5 M in H2O
• Pharmacopeia: testing & handling conforms to Pharmacopeia
• Product Line: BioUltra
• Linear Formula: NaF

DETAILS

MP Biomedicals - 02194864

ACS Reagent Grade
Purity: >99%
For U.S. domestic market only.
NOT FOR EXPORT

Sigma Aldrich - 71519

Other Notes
Enzyme inhibitor e.g. pyrimidine nucleoside monophosphate kinase1; Stimulates cardiac adenylate cyclase and can be used to differentiate the isoenzymes2

Sigma Aldrich - 919

Application
For use in inhibiting α-naphthyl acetate reaction on monocytes. Optional reagent in Sigma Esterase Procedure 91A.
Other Notes
2 g/dL

Sigma Aldrich - 450022

Packaging
5, 25 g in glass bottle
Application
Starting material for solid state preparation of Na3MnF6 for further high pressure structural determination studies.1

Sigma Aldrich - 215309

Packaging
10, 50, 250 g in poly bottle
Application
Starting material for solid state preparation of Na3MnF6 for further high pressure structural determination studies.1

Sigma Aldrich - 34247

General description
Visit our Titration Center to learn more.
Packaging
The suffix -VP or -VOLPAC in the product number indicates packaging in 5 or 10 L VOLPAC containers.

Sigma Aldrich - 80373

Analysis Note
Exact concentration, expiry date, traceability and detailed information on certification can be found on the certificate and certification report, included in each package. Content and expiry date on label.
Preparation Note
prepared with high purity NaF and high purity water (18 MOhm, filtered 0.22 μm)

Sigma Aldrich - 47072

General description
Visit our Sensor Applications portal to learn more.
Preparation Note
prepared with NaF and H2O

Sigma Aldrich - 318930

General description
Visit our Titration Center to learn more.
Packaging
500 mL in poly bottle

Sigma Aldrich - 201154

Application
Starting material for solid state preparation of Na3MnF6 for further high pressure structural determination studies.1
Packaging
5, 100, 500 g in poly bottle

Sigma Aldrich - S1504

包装
100, 500 g in glass bottle
法律信息
ReagentPlus 注册商标 Sigma-Aldrich Co. LLC

Sigma Aldrich - 28-2690

Suitability
standard

REFERENCES

• Reviews: Fluoride ion as a base in organic synthesis: Chem. Rev., 80, 429 (1980). Alkali metal fluorides in organic synthesis: Synthesis, 169 (1983). See also Potassium fluoride, 14130.