potassium fluoride

• ChemBase ID: 98881
• Molecular Formular: FK
• Molecular Mass: 58.0967032
• Monoisotopic Mass: 57.9621099
• SMILES: [K+].[F-]
• Canonical SMILES: [F-].[K+]
• InChI: InChI=1S/FH.K/h1H;/q;+1/p-1
• InChIKey: NROKBHXJSPEDAR-UHFFFAOYSA-M

NAMES AND DATABASE IDS

Names

• IUPAC name: potassium fluoride
• IUPAC Traditional name: potassium ion fluoride; potassium fluoride
• Synonyms: Potassium fluoride, anhydrous 99%; Potassium fluoride on aluminum oxide; Potassium fluoride solution; Potassium fluoride; Potassium fluoride, anhydrous; Potassium fluoride, ACS; Potassium fluoride; POTASSIUM FLUORIDE ACS REAGENT GRADE; Potassium fluoride on Celite®; Potassium fluoride on alumina; 氟化钾 溶液; 氟化钾, 无水; 氟化钾, ACS; 氟化钾; Celite® 负载氟化钾; 氧化铝负载氟化钾

Database IDs

• CAS Number: 7789-23-3; 7789-23-3(anhydrous); 13455-21-1(dihydrate)
• EC Number: 232-151-5
• MDL Number: MFCD00011398
• Beilstein Number: 3902818
• Merck Index: 147632
• PubChem SID: 24881818; 24868456; 24855751; 24881817; 24881821; 24858608; 24882079; 24859011; 24865142; 162085223; 24852889; 24881819; 24853749
• PubChem CID: 522689
• CHEMBL: 1644027
• Chemspider ID: 23006
• Unique Ingredient Identifier: 9082WG1G3F
• Wikipedia Title: Potassium_fluoride

CALCULATED PROPERTIES

• Acid pKa: 3.17
• H Acceptors: 0
• H Donor: 0
• LogD (pH = 5.5): 0.3684526
• LogD (pH = 7.4): 0.36924794
• Log P: 0.14883864
• Molar Refractivity: 0.8725 cm^3
• Polarizability: 0.45069772 Å^3
• Polar Surface Area: 0.0 Å^2
• Rotatable Bonds: 0
• Lipinski's Rule of Five: true

PROPERTIES

Physical Property

• Solubility: anhydrous: ; 92 g/100 mL (18 °C) ; 102 g/100 mL (25 °C)

  ---

  dihydrate: ; 349.3 g/100 mL (18 °C) in water; H2O: soluble1 M at 20 °C, clear, colorless; Solubility in water at 21 (96g/100ml). Freely soluble in boiling water. Soluble in aqueous HF, liquid NH3. Insoluble in anhydrous alcohol; soluble in HF ; insoluble in alcohol
• Apperance: Crystalline; powder; Powder; powder and chunks; solid; spray-dried; white crystals
• Melting Point: 846°C; 858 °C (anhydrous) ; 41 °C (dihydrate) ; 19.3 °C (trihydrate); 858 °C(lit.); 859.9°C; 859°C
• Boiling Point: 1500°C; 1502 °C; 1505°C; 1505°C
• Flash Point: Non-flammable
• Density: 2.48; 2.48 g/cm^3; 2.48 g/ml
• Refractive Index: 1.363
• Absorption Wavelength: λ: 260 nm Amax: 0.01; λ: 280 nm Amax: 0.01
• pH: 7.0-8.5 (25 °C, 1 M in H2O)

Safety Information

• Storage Condition: Room Temperature (15-30°C)
• Storage Warning: Hygroscopic; Toxic/Hygroscopic/Store under Argon
• RTECS: TT0700000
• European Hazard Symbols: Corrosive (C); Toxic (T); Harmful (Xn)
• UN Number: 1812; UN1812
• German water hazard class: 1; 3; nwg
• Hazard Class: 6.1
• Packing Group: 3; III
• Australian Hazchem: 2Z
• Risk Statements: 20/21/22-34; 22; 23/24/25; R:23/24/25; R23/24/25
• Safety Statements: 26-27-28.1-36/37/39-45; 26-45; 36/37-45; S:26-45; S1/2, S26, S45
• EU Classification: T2
• EU Hazard Identification Number: 6.1B
• Emergency Response Guidebook(ERG) Number: 154
• TSCA Listed: 是
• EU Index: 009-005-00-2
• GHS Pictograms: GHS06; GHS07
• GHS Signal Word: Danger; Warning
• NFPA704:
  

  0

  3

  1
• LD50: 245 mg/kg (oral, guinea pig)
• GHS Hazard statements: H301 + H311 + H331; H301-H311-H331; H302
• GHS Precautionary statements: P261-P280-P301 + P310-P311; P261-P301+P310-P361-P302+P352-P405-P501A
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves; Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges; Eyeshields, Gloves, half-mask respirator (US), multi-purpose combination respirator cartridge (US); Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RID/ADR: UN 1812 6.1/PG 3

Product Information

• Purity: ≥99%; ≥95.0%; ≥98.5%; ≥99%; ≥99.0%; ≥99.0% (F); ≥99.5% (F); ≥99.99% trace metals basis; 98%; 99%; 99% min; 99.9% (metals basis); 99.99% (metals basis); 99.99% trace metals basis
• Concentration: 0.2 M in D2O (99.8 atom % D)
• Grade: ACS; ACS reagent; anhydrous; NMR reference standard; puriss.; puriss. p.a.; purum p.a.; REAGENT; reagent grade; SAJ first grade; SAJ special grade; technical grade
• Compostion: water, 90%
• Impurities: ≤0.01 meq/g Titr. base; ≤0.01% free acid (as HF); ≤0.01% free alkali (as KOH); ≤0.03 meq/g Titr. acid; ≤0.1% K2SiF6; ≤0.1% potassium fluoro silicate (K2SiF6); ≤0.1% potassium hexafluorosilicate; insoluble matter, passes filter test
• Cation Traces: Ag: ≤5 mg/kg; Al: ≤5 mg/kg; As: ≤1 mg/kg; As: ≤5 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤10 mg/kg; Ca: ≤50 mg/kg; Cd: ≤5 mg/kg; Cd: ≤50 mg/kg; Co: ≤5 mg/kg; Co: ≤50 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Cu: ≤50 mg/kg; Fe: ≤0.001%; Fe: ≤20 mg/kg; Fe: ≤5 mg/kg; Fe: ≤50 mg/kg; heavy metals (as Pb): ≤0.001%; Li: ≤5 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; Na: ≤0.2%; Na: ≤2000 mg/kg; Na: ≤5000 mg/kg; Ni: ≤5 mg/kg; Ni: ≤50 mg/kg; Pb: ≤10 mg/kg; Pb: ≤5 mg/kg; Pb: ≤50 mg/kg; Sr: ≤5 mg/kg; Tl: ≤5 mg/kg; Zn: ≤5 mg/kg; Zn: ≤50 mg/kg
• Antion Traces: chloride (Cl-): ≤0.005%; chloride (Cl-): ≤100 mg/kg; chloride (Cl-): ≤50 mg/kg; sulfate (SO42-): ≤0.005%; sulfate (SO42-): ≤100 mg/kg; sulfate (SO42-): ≤1000 mg/kg; sulfate (SO42-): ≤500 mg/kg
• Contains: 0.5% SiO2 as anticaking agent
• Loss on Drying: ≤0.3% loss on ignition, 500 °C,15 min; ≤0.5% loss on ignition, 500 °C, 2 h
• Extent of Labeling: ~5.5 mmol/g F- loading; 40 wt. % loading; 50 wt. % loading
• Quality: purified
• NMR tube O.D. × L: 10 mm × 8 in.
• λ: 1 M in H2O
• Product Line: BioUltra
• Linear Formula: KF; KF-Al2O3; KF-Celite

DETAILS

MP Biomedicals - 02194873

ACS Reagent Grade
Purity: >99%
NOT FOR EXPORT

Apollo Scientific Ltd - PC6267S

Spray-dried highly active source of fluoride, suitable for halex reactions. LOD <0.1%

Sigma Aldrich - 60238

Application
A versatile fluoride ion source used in a study of ion-specific swelling and de-swelling of ampholytic polymer gels,1 in the room temperature oxidation of noble metals in HF,2 and in the measurement of electronic polarizabilities of ions in polymers of alkali halides.3
Other Notes
Inhibitor of pyrophosphatase, hence prevents loss of ATP by hydrolytic cleavage of the pyrophosphate bond in the assay of amidophosphoribosyltransferase4; Strongly inhibits polypeptide chain initiation in the reticulocyte lysate cell-free system5

Sigma Aldrich - P1179

Application
多功能氟离子源，用于研究两性聚合物凝胶的离子特异性溶胀和消溶胀，1贵金属在 HF 中的室温氧化，2以及测量卤化碱聚合物中离子的电子极化率。3

Sigma Aldrich - 60244

Other Notes
Supported fluoride, useful as catalyst and supported base for elimination, addition and condensation reactions 1,2; Potassium fluoride on aluminum oxide was shown by L. Weinstock et al. to be in reality KOH and K3AlF6 on aluminum oxide3
Packaging
25, 100 g in poly bottle

Sigma Aldrich - 262552

Packaging
10, 100 g in poly bottle
Legal Information
Celite is a registered trademark of Imerys Minerals California, Inc.

Sigma Aldrich - 01132

Application
A versatile fluoride ion source used in a study of ion-specific swelling and de-swelling of ampholytic polymer gels,1 in the room temperature oxidation of noble metals in HF,2 and in the measurement of electronic polarizabilities of ions in polymers of alkali halides.3

Sigma Aldrich - 215384

Application
A versatile fluoride ion source used in a study of ion-specific swelling and de-swelling of ampholytic polymer gels,1 in the room temperature oxidation of noble metals in HF,2 and in the measurement of electronic polarizabilities of ions in polymers of alkali halides.3
Packaging
1 kg in poly bottle
250 g in poly bottle

Sigma Aldrich - 449148

Application
A versatile fluoride ion source used in a study of ion-specific swelling and de-swelling of ampholytic polymer gels,4 in the room temperature oxidation of noble metals in HF,5 and in the measurement of electronic polarizabilities of ions in polymers of alkali halides.6
A versatile fluoride ion source used recently in a study of ion-specific swelling and de-swelling of ampholytic polymer gels,1 in the room temperature oxidation of noble metals in HF,2 and in the measurement of electronic polarizabilities of ions in polymers of alkali halides.3
Packaging
5, 25 g in glass bottle

Sigma Aldrich - 60240

Application
A versatile fluoride ion source used in a study of ion-specific swelling and de-swelling of ampholytic polymer gels,1 in the room temperature oxidation of noble metals in HF,2 and in the measurement of electronic polarizabilities of ions in polymers of alkali halides.3

Sigma Aldrich - 316385

Packaging
25, 100 g in poly bottle

Sigma Aldrich - 60239

Application
A versatile fluoride ion source used in a study of ion-specific swelling and de-swelling of ampholytic polymer gels,1 in the room temperature oxidation of noble metals in HF,2 and in the measurement of electronic polarizabilities of ions in polymers of alkali halides.3
Other Notes
Reagent for the decomposition of silicates by fusion4,5

Sigma Aldrich - 229814

Application
A versatile fluoride ion source used in a study of ion-specific swelling and de-swelling of ampholytic polymer gels,1 in the room temperature oxidation of noble metals in HF,2 and in the measurement of electronic polarizabilities of ions in polymers of alkali halides.3
Packaging
10, 100 g in poly bottle

Sigma Aldrich - 24-4610

Application
A versatile fluoride ion source used in a study of ion-specific swelling and de-swelling of ampholytic polymer gels,1 in the room temperature oxidation of noble metals in HF,2 and in the measurement of electronic polarizabilities of ions in polymers of alkali halides.3

Sigma Aldrich - 307599

Application
A versatile fluoride ion source used in a study of ion-specific swelling and de-swelling of ampholytic polymer gels,3 in the room temperature oxidation of noble metals in HF,4 and in the measurement of electronic polarizabilities of ions in polymers of alkali halides.5
Fluorinating agent with decreased moisture sensitivity and enhanced reactivity.1,2
Packaging
1 kg in poly bottle
50, 250 g in poly bottle

Sigma Aldrich - 24-4620

Application
A versatile fluoride ion source used in a study of ion-specific swelling and de-swelling of ampholytic polymer gels,1 in the room temperature oxidation of noble metals in HF,2 and in the measurement of electronic polarizabilities of ions in polymers of alkali halides.3

Sigma Aldrich - 402931

Application
A versatile fluoride ion source used in a study of ion-specific swelling and de-swelling of ampholytic polymer gels,1 in the room temperature oxidation of noble metals in HF,2 and in the measurement of electronic polarizabilities of ions in polymers of alkali halides.3
Packaging
12 kg in poly drum
5, 100, 500 g in poly bottle

Sigma Aldrich - 01133

Application
A versatile fluoride ion source used in a study of ion-specific swelling and de-swelling of ampholytic polymer gels,1 in the room temperature oxidation of noble metals in HF,2 and in the measurement of electronic polarizabilities of ions in polymers of alkali halides.3

REFERENCES

• KF can also behave as a base in a wide variety of applications:
• In the Henry reaction of 1-nitropropane with an aldehyde: Org. Synth. Coll., 9, 242 (1998). For the methylenation of catechols with Dibromomethane, A10456, in DMF: Tetrahedron Lett., 3361 (1976). In an olefination reaction with 2,2,2-Trifluoroacetophenone, A11403: J. Org. Chem., 59, 2898 (1994). In combination with 18-crown-6 for selective removal of Fmoc protecting groups under mild conditions: Synth. Commun., 24, 187 (1994).
• Reviews: Fluoride ion as a base in organic synthesis: Chem. Rev., 80, 429 (1980). Alkali metal fluorides in organic synthesis: Synthesis, 169 (1983). See also Cesium fluoride, 12885.
• An active form of KF has been prepared by recrystallization from methanol followed by drying at 100^oC: Tetrahedron, 51, 6363 (1995).
• Widely used in "halex" fluorination reactions for the preparation of aryl fluorides from the corresponding chlorides by heating in a dipolar aprotic solvent, e.g. tetramethylene sulfone: J. Fluorine Chem., 46, 529 (1990). Other solvents including DMSO, DMA and NMP are also successfully employed. For a review of the preparation of aryl fluorides by halogen exchange, see: Chem. Ind. (London), 518 (1986). Aryl nitro groups can also be displaced in suitable molecules: J. Org. Chem., 56, 6406 (1991). Relative rates for aromatic fluorodenitration in different solvents were found to be: DMSO > tetramethylene sulfoxide > DMA > NMP > tetramethylene sulfone >> acetonitrile > DME: J. Fluorine Chem., 35, 591 (1987).
• For use in trifluoromethylation of aromatic, allylic and ɑ-carboxy halides, see Methyl chlorodifluoroacetate, A18623.
• Has been used in cleavage of silyl protecting groups under phase-transfer conditions (see tert-Butyldimethylchlorosilane, A13064): J. Am. Chem. Soc., 90, 4462, 4464 (1968); 96, 2250 (1974); J. Chem. Soc., Chem. Commun., 514 (1979).